Since 2000-01, Clarence Seedorf has made the most appearances by a Milan player in the Champions League, with 89 appearances.

most appearances by a player for milan after 2000

	NAME	M	Rating	MIN	START	G	G/M	A	G+A	PK	FK	SH	SOT	WOOD	TCH	TCH-BOX	OFF
1	Clarence Seedorf C. Seedorf	89		6,747	79	8	0.09			0
2	Alessandro Nesta A. Nesta	78		6,677	77	0	0.00			0
3	Andrea Pirlo A. Pirlo	78		6,557	75	7	0.09			0
4	Massimo Ambrosini M. Ambrosini	76		4,865	53	1	0.01			0
5	Gennaro Gattuso G. Gattuso	74		6,216	71	1	0.01			0
6	Paolo Maldini P. Maldini	73		5,967	68	1	0.01			0
7	Dida	72		6,429	72	0	0.00			0
8	Kaká	62		5,164	60	25	0.40			4
9	Filippo Inzaghi F. Inzaghi	55		3,438	38	29	0.53			0
10	Andriy Shevchenko A. Shevchenko	53		4,496	52	28	0.53			3
11	Sérgio dos Santos S. dos Santos	49		2,319	22	2	0.04			0
12	Kakha Kaladze K. Kaladze	46		3,577	38	0	0.00			0
13	Christian Abbiati C. Abbiati	42		3,635	41	0	0.00			0
14	Rui Costa R. Costa	35		1,847	19	0	0.00			0
15	Alessandro Costacurta A. Costacurta	35		2,462	28	0	0.00			0
16	Cafu	33		2,570	27	0	0.00			0
17	Theo Hernández T. Hernández	32	6.82	2,798	32	0	0.00	2	2	0	0	39	7	5	2,175	50	7
18	Daniele Bonera D. Bonera	31		2,214	24	0	0.00			0
19	Rafael Leão R. Leão	30	6.85	2,448	29	6	0.20	6	12	0	0	47	19	4	1,256	160	8
20	Ignazio Abate I. Abate	30		2,178	24	0	0.00			0
21	Fikayo Tomori F. Tomori	29	6.56	2,349	27	1	0.03	1	2	0	0	11	4	1	1,790	11	0
22	Mike Maignan M. Maignan	26	7.01	2,292	26	0	0.00	0	0	0	0	0	0	0	1,074	1	0
23	Alberto Gilardino A. Gilardino	26		1,247	14	4	0.15			0
24	Robinho	24		1,361	15	4	0.17			0
25	Olivier Giroud O. Giroud	23	6.35	1,712	21	6	0.26	4	10	2	0	44	26	0	601	86	17