Francesco Totti has the most career goals by a Roma player in Serie A, with 250 goals.

most goals by a player in roma history

	NAME	G	M	MIN	START	G/M	A	G+A	PK	FK	SH	SOT	WOOD	TCH	TCH-BOX	OFF
1	Francesco Totti F. Totti	250	618	47,054	540	0.40	46	296	71
2	Roberto Pruzzo R. Pruzzo	106	237	20,023	232	0.45			21
3	Edin Džeko E. Džeko	85	199	15,285	166	0.43	34	119	3	0	737	294	27	7,011	1,108	99
4	Amedeo Amadei A. Amadei	85	182	16,380	182	0.47			2
5	Vincenzo Montella V. Montella	83	192	11,964	132	0.43			8
6	Abel Eduardo Balbo A. Eduardo Balbo	78	149	12,076	140	0.52			18
7	Rodolfo Volk R. Volk	78	127	11,348	127	0.61			0
8	Pedro Waldemar Manfredini P. Waldemar Manfredini	77	130	11,700	130	0.59			8
9	Dino da Costa D. da Costa	72	149	13,365	149	0.48			0
10	Marco Delvecchio M. Delvecchio	62	231	14,649	169	0.27			0
11	Stephan El Shaarawy S. El Shaarawy	51	246	13,244	143	0.21	25	76	0	1	426	168	7	8,352	628	72
12	Agostino Di Bartolomei A. Di Bartolomei	50	237	20,719	230	0.21			12
13	Giuseppe Giannini G. Giannini	49	318	26,323	294	0.15			10
14	Mirko Vučinić M. Vučinić	46	147	9,443	107	0.31	3	49	3
15	Rudolf Völler R. Völler	45	142	12,317	140	0.32			7
16	Cesare Augusto Fasanelli C. Augusto Fasanelli	44	121	10,890	121	0.36			0
17	Daniele De Rossi D. De Rossi	43	459	37,196	428	0.09	21	64	4
18	Enrique Guaita E. Guaita	43	60	5,400	60	0.72			6
19	Miguel Ángel Pantó M. Ángel Pantó	41	129	11,485	129	0.32			6
20	Raffaele Costantino R. Costantino	41	157	14,128	157	0.26			1
21	Mancini	40	154	12,010	136	0.26			4
22	Giancarlo Galli G. Galli	40	94	8,415	94	0.43			0
23	Lorenzo Pellegrini L. Pellegrini	39	239	17,317	202	0.16	34	73	8	3	476	164	21	11,907	544	39
24	Antonio Cassano A. Cassano	39	118	7,567	85	0.33			0
25	Bruno Conti B. Conti	37	304	24,247	280	0.12			0