Since 1999-00, Harry Kane has the most goals in the Premier League, with 213 goals.

most goals by a player scored from 2000s

	NAME	G	RTG	M	MIN	START	G/M	A	G+A	PK	FK	SH	SOT	WOOD	TCH	TCH-BOX	OFF
1	Harry Kane H. Kane	213		320	26,953	302	0.67	47	260	33
2	Wayne Rooney W. Rooney	208		491	38,027	421	0.42	100	308	23
3	Mohamed Salah M. Salah	190		311	25,553	287	0.61	89	279	35
4	Sergio Agüero S. Agüero	184		275	19,869	235	0.67	47	231	27
5	Thierry Henry T. Henry	175		258	21,313	235	0.68	74	249	23
6	Frank Lampard F. Lampard	167		525	42,617	478	0.32	96	263	42
7	Jermain Defoe J. Defoe	162		496	32,631	347	0.33	33	195	14
8	Jamie Vardy J. Vardy	145		342	26,555	301	0.42	47	192	27	0	678	326	21	7,582	1,129	303
9	Robin van Persie R. van Persie	144		280	20,119	227	0.51	52	196	15
10	Son Heung-min S. Heung-min	127		333	24,132	276	0.38	71	198	4	1	725	338	30	13,231	1,414	177
11	Robbie Keane R. Keane	126		349	24,461	273	0.36	37	163	17
12	Raheem Sterling R. Sterling	123		396	28,558	322	0.31	64	187	3
13	Romelu Lukaku R. Lukaku	121		278	20,670	225	0.44	33	154	7
14	Steven Gerrard S. Gerrard	121		492	40,728	462	0.25	89	210	31
15	Michael Owen M. Owen	113		258	17,379	192	0.44	16	129	11
16	Sadio Mané S. Mané	112		263	20,668	237	0.43	38	150	0	0	629	263	16	12,945	1,207	165
17	Peter Crouch P. Crouch	107		468	28,485	310	0.23	58	165	1
18	Alan Shearer A. Shearer	107		225	19,550	220	0.48	25	132	28
19	Darren Bent D. Bent	106		276	20,088	216	0.38	15	121	17
20	Didier Drogba D. Drogba	104		254	17,561	187	0.41	54	158	4
21	Cristiano Ronaldo C. Ronaldo	103		236	17,523	188	0.44	37	140	14
22	Nicolas Anelka N. Anelka	102		299	23,713	268	0.34	36	138	7
23	Emmanuel Adebayor E. Adebayor	97		242	17,935	199	0.40	36	133	10
24	Erling Haaland E. Haaland	96	7.19	106	8,853	102	0.91	17	113	17	0	390	200	12	2,426	683	18
25	Yakubu Aiyegbeni Y. Aiyegbeni	95		252	19,009	216	0.38	26	121	18