Southampton have lost the most games by a club with exactly 0 relegations and in the Premier League in a season, with 23 losses in 1993-94.

most losses without relegation in a season premier league

	CLUB	L	RELS	SEASON	M	W	D	G	GC	xG	xGA	SH	SOT	PASS-ATT	PASS	POSS%	FOUL	YC	RC
1	Southampton	23	0	1993-94	42	12	7	49	66									43	1
2	Tottenham	22	0	2024-25	38	11	5	64	65	59.49	66.47	497	185	18,136	15,454	54.7	446	72	1
3	Everton	22	0	1993-94	42	12	8	42	63									33	0
4	Bournemouth	21	0	2022-23	38	11	6	37	71	40.22	66.36	357	133	13,939	10,827	40.0	390	68	0
5	Everton	21	0	2021-22	38	11	6	43	66	43.24	58.93	438	138	12,898	9,513	39.6	368	82	6
6	Aston Villa	21	0	2019-20	38	9	8	41	67			459	151	13,668	10,513	43.9	451	70	1
7	Crystal Palace	21	0	2016-17	38	12	5	50	63			439	138	13,542	9,944	45.3	470	79	0
8	Swansea	21	0	2016-17	38	12	5	45	70			405	145	16,131	12,723	47.9	401	56	0
9	Hull City	21	0	2013-14	38	10	7	38	53			427	132	15,267		45.3	421	56	4
10	QPR	21	0	2011-12	38	10	7	43	66			539	150	13,394		45.1	409	60	9
11	Sunderland	21	0	2007-08	38	11	6	36	59			483	137	12,736		47.5	517	69	4
12	West Ham	21	0	2006-07	38	12	5	35	59			461	134	13,189		50.3	588	87	2
13	Man City	21	0	2005-06	38	13	4	43	48									64	4
14	Wolves	20	0	2024-25	38	12	6	54	69	44.75	59.01	431	160	16,267	13,455	48.0	481	79	2
15	Nottm Forest	20	0	2023-24	38	9	9	49	67	50.81	54.74	451	148	14,176	11,178	40.2	428	82	3
16	West Ham	20	0	2022-23	38	11	7	42	55	51.16	54.84	474	145	14,604	11,472	41.7	362	44	0
17	Brighton	20	0	2018-19	38	9	9	35	60			371	108	14,345	10,773	42.0	463	62	4
18	Burnley	20	0	2018-19	38	11	7	45	68			360	116	13,240	9,382	40.7	360	75	1
19	Burnley	20	0	2016-17	38	11	7	39	55			391	120	12,558	8,521	40.2	429	67	2
20	Watford	20	0	2016-17	38	11	7	40	68			422	144	14,049	10,397	46.1	517	90	5
21	Aston Villa	20	0	2014-15	38	10	8	31	57			418	125	16,515	13,050	49.0	403	76	7
22	Aston Villa	20	0	2013-14	38	10	8	39	61			431	135	13,856		43.7	491	78	0
23	Sunderland	20	0	2013-14	38	10	8	41	60			491	138	14,457		46.2	449	70	8
24	West Ham	20	0	2013-14	38	11	7	40	51			422	122	12,364		42.6	407	66	5
25	Wolves	20	0	2010-11	38	11	7	46	66			459	139	14,823		50.6	477	64	2