Javier Zanetti has made the most career appearances by an Inter player in the Champions League, with 97 appearances.

	NAME	M	RTG	MIN	START	G	G/M	A	G+A	PK	FK	SH	SOT	WOOD	TCH	TCH-BOX	OFF
1	Javier Zanetti J. Zanetti	97		8,265	91	2	0.02			0
2	Esteban Cambiasso E. Cambiasso	62		5,000	56	6	0.10			0
3	Lautaro Martínez L. Martínez	60		4,056	48	24	0.40	6	30	2	0	169	69	9	1,667	267	26
4	Iván Córdoba I. Córdoba	60		5,068	54	1	0.02			0
5	Dejan Stanković D. Stanković	56		4,195	49	8	0.14			0
6	Júlio César J. César	52		4,636	52	0	0.00			0
7	Nicolò Barella N. Barella	51		3,873	43	4	0.08	4	8	0	0	55	12	4	2,737	80	10
8	Alessandro Bastoni A. Bastoni	50		3,885	45	0	0.00	6	6	0	0	16	2	0	3,401	30	1
9	Marco Materazzi M. Materazzi	49		3,661	44	1	0.02			0
10	Stefan de Vrij S. de Vrij	47		3,598	41	1	0.02	2	3	0	0	12	4	0	2,945	22	0
11	Maicon	44		3,899	44	3	0.07			0
12	Wálter Samuel W. Samuel	40		3,401	39	3	0.08			0
13	Tarcisio Burgnich T. Burgnich	40		3,600	40	0	0.00			0
14	Hakan Çalhanoğlu H. Çalhanoğlu	39	7.25	2,780	34	7	0.18	6	13	5	1	57	15	2	2,339	18	1
15	Denzel Dumfries D. Dumfries	39	6.42	2,892	33	5	0.13	5	10	0	0	41	13	1	1,571	133	11
16	Giacinto Facchetti G. Facchetti	39		3,510	39	6	0.15			0
17	Federico Dimarco F. Dimarco	38	6.90	2,155	26	1	0.03	6	7	0	0	46	11	1	1,587	62	5
18	Matteo Darmian M. Darmian	38		2,125	23	1	0.03	0	1	0	0	15	5	0	1,245	39	9
19	Alessandro Mazzola A. Mazzola	38		3,420	38	17	0.45			2
20	Francesco Toldo F. Toldo	37		3,330	37	0	0.00			0
21	Henrikh Mkhitaryan H. Mkhitaryan	34	6.95	2,355	29	2	0.06	0	2	0	0	33	11	1	1,512	38	6
22	Marcelo Brozović M. Brozović	34		2,608	29	1	0.03	2	3	0	0	27	3	1	2,533	13	0
23	Julio Cruz J. Cruz	34		1,729	18	13	0.38			1
24	Jair da Costa J. da Costa	34		2,972	34	11	0.32			0
25	Giuliano Sarti G. Sarti	32		2,880	32	0	0.00			0