Between the 1941 and 1950 seasons, Bill Nicholson hit the most home runs for the Cubs, with 175 home runs.

	NAME	HR	G	AB	R	H	2B	3B	RBI	BB	HBP	SO	SB	PA	TB	XBH	SH	GIDP	AVG	OBP	SLG	OPS	wRC	WRAA	wOBA	wRC+	BRAA
1	Bill Nicholson B. Nicholson	175	1,156	4,146	623	1,112	206	41	697	626	40	588	24	4,826	1,925	422	14	47	.268	.369	.464	.834	745	215.7	.391	135	194.4
2	Andy Pafko A. Pafko	114	911	3,389	460	1,001	157	37	549	315	44	233	27	3,796	1,574	308	48	87	.295	.363	.464	.827	571	136.2	.383	124	115.6
3	Hank Sauer H. Sauer	59	241	897	144	252	49	3	186	97	6	114	1	1,001	484	111	1	20	.281	.355	.540	.895	167	44.5	.401	132	40.9
4	Phil Cavarretta P. Cavarretta	59	1,234	4,389	679	1,320	241	67	607	613	20	368	32	5,082	1,872	367	60	66	.301	.389	.427	.815	763	200.7	.385	130	177.9
5	Roy Smalley R. Smalley	33	413	1,395	140	323	53	23	156	108	9	267	4	1,522	521	109	10	34	.232	.291	.373	.664	140	-44.5	.307	74	-49.7
6	Clyde McCullough C. McCullough	24	572	1,734	173	436	70	16	178	140	6	231	21	1,909	610	110	29	50	.251	.310	.352	.661	186	-24.1	.314	87	-29.1
7	Peanuts Lowrey P. Lowrey	22	726	2,595	331	722	105	32	311	224	3	142	41	2,888	957	159	66	54	.278	.336	.369	.705	322	6.7	.335	97	-9.8
8	Dom Dallessandro D. Dallessandro	21	571	1,511	191	409	84	16	256	249	2	121	10	1,771	588	121	9	42	.271	.375	.389	.764	242	47.3	.365	121	42.7
9	Stan Hack S. Hack	21	851	3,215	538	964	162	26	232	551	2	209	44	3,815	1,241	209	47	29	.300	.403	.386	.789	557	143.9	.380	129	128
10	Bill Serena B. Serena	18	139	472	59	112	23	4	68	72	1	84	1	547	197	45	2	11	.237	.339	.417	.757	69	1.3	.349	99	-0.5
11	Lou Stringer L. Stringer	17	346	1,127	130	273	44	10	113	116	1	175	6	1,272	388	71	28	18	.242	.314	.344	.658	126	-14.4	.314	90	-14.7
12	Babe Dahlgren B. Dahlgren	16	116	415	54	113	21	1	65	47	1	41	2	463	184	38	0	11	.272	.348	.443	.791	66	12.5	.367	124	13.1
13	Bob Scheffing B. Scheffing	16	437	1,170	92	311	51	9	165	80	2	111	6	1,262	428	76	10	37	.266	.314	.366	.680	128	-16.7	.319	85	-22
14	Lou Novikoff L. Novikoff	15	339	1,058	107	298	44	10	135	63	5	69	4	1,135	407	69	9	34	.282	.325	.385	.710	129	7.5	.335	104	5
15	Rube Walker R. Walker	14	209	556	47	138	19	2	64	51	2	69	0	609	203	35	0	15	.248	.314	.365	.679	61	-12.7	.318	81	-14.7
16	Eddie Waitkus E. Waitkus	13	394	1,545	198	455	79	21	134	98	6	53	17	1,669	615	113	20	29	.294	.339	.398	.737	199	10.7	.344	102	2.9
17	Wayne Terwilliger W. Terwilliger	12	169	592	74	141	24	4	42	59	6	85	13	667	209	40	10	9	.238	.314	.353	.667	64	-18	.312	76	-20.3
18	Claude Passeau C. Passeau	10	212	521	41	97	13	2	46	8	0	131	0	558	144	25	29	7	.186	.198	.276	.475	18	-42.6	.222	30	-44.8
19	Hank Edwards H. Edwards	9	99	286	38	91	19	5	42	29	0	35	0	316	147	33	1	6	.318	.381	.514	.895	54	15.7	.406	136	14.4
20	Marv Rickert M. Rickert	9	190	555	56	130	18	3	63	44	1	76	3	606	181	30	6	15	.234	.292	.326	.618	49	-16.2	.295	75	-18.7
21	Hal Jeffcoat H. Jeffcoat	8	308	1,015	117	263	47	11	86	50	2	139	27	1,087	356	66	20	22	.259	.295	.351	.646	94	-36.2	.301	71	-39.8
22	Don Johnson D. Johnson	8	511	1,935	219	528	89	6	175	112	8	171	26	2,102	653	103	47	34	.273	.315	.337	.653	200	-28.8	.311	83	-43.2
23	Mickey Livingston M. Livingston	8	192	544	46	138	25	3	62	52	6	38	3	613	193	36	11	18	.254	.326	.355	.680	64	-0.6	.327	95	-4.6
24	Rip Russell R. Russell	8	108	319	33	78	10	0	42	18	0	26	0	344	112	18	7	6	.245	.285	.351	.636	31	-5.4	.302	85	-5.7
25	Frank Secory F. Secory	7	90	156	20	37	5	0	35	14	0	21	1	177	63	12	7	3	.237	.300	.404	.704	20	0.6	.332	99	-0.5