| NAME | G | W | L | W% | GS | ERA | SO | CG | SHO | SV | IP | H | ER | R | HR | BB | HBP | GF | IBB | TBF | WP | K/9 | BB/9 | K/BB | HR/9 | K% | BB% | WHIP | BABIP | RA | ERA- | FIP | FIP- | H/9 | PRAA | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | R. Faber | 669 | 254 | 213 | .544 | 483 | 3.15 | 1,471 | 273 | 29 | 27 | 4086.2 | 4,106 | 1,430 | 1,813 | 111 | 1,213 | 103 | 134 | 17,104 | 52 | 3.24 | 2.67 | 1.21 | 0.24 | 8.6 | 7.1 | 1.30 | .281 | 3.99 | 84 | 3.43 | 93 | 9.04 | 124.6 | ||
| 2 | T. Lyons | 594 | 260 | 230 | .531 | 484 | 3.67 | 1,073 | 356 | 27 | 25 | 4161.0 | 4,489 | 1,696 | 2,056 | 222 | 1,121 | 31 | 91 | 17,797 | 55 | 2.32 | 2.42 | 0.96 | 0.48 | 6.0 | 6.3 | 1.35 | .278 | 4.45 | 85 | 4.01 | 95 | 9.71 | 91.7 | ||
| 3 | W. Wood | 578 | 163 | 148 | .524 | 286 | 3.18 | 1,332 | 113 | 24 | 57 | 2524.1 | 2,422 | 891 | 1,044 | 193 | 671 | 57 | 174 | 62 | 10,472 | 63 | 4.75 | 2.39 | 1.99 | 0.69 | 12.7 | 6.4 | 1.23 | .271 | 3.72 | 87 | 3.33 | 91 | 8.64 | 87.1 | |
| 4 | M. Thornton | 512 | 31 | 35 | .470 | 0 | 3.28 | 486 | 0 | 0 | 23 | 463.1 | 400 | 169 | 186 | 33 | 154 | 13 | 116 | 29 | 1,918 | 17 | 9.44 | 2.99 | 3.16 | 0.64 | 25.3 | 8.0 | 1.20 | .298 | 3.61 | 74 | 3.01 | 68 | 7.77 | 72.1 | |
| 5 | B. Pierce | 456 | 186 | 152 | .550 | 391 | 3.19 | 1,796 | 183 | 35 | 21 | 2931.0 | 2,643 | 1,038 | 1,153 | 241 | 1,052 | 24 | 43 | 31 | 12,278 | 41 | 5.51 | 3.23 | 1.71 | 0.74 | 14.6 | 8.6 | 1.26 | .262 | 3.54 | 82 | 3.42 | 88 | 8.12 | 156 | |
| 6 | E. Walsh | 426 | 195 | 125 | .609 | 312 | 1.81 | 1,732 | 249 | 57 | 35 | 2946.1 | 2,324 | 591 | 864 | 23 | 608 | 51 | 104 | 11,331 | 75 | 5.29 | 1.86 | 2.85 | 0.07 | 15.3 | 5.4 | 1.00 | .258 | 2.64 | 69 | 2.01 | 79 | 7.10 | 166.4 | ||
| 7 | B. Thigpen | 424 | 28 | 33 | .459 | 0 | 3.26 | 362 | 0 | 0 | 201 | 541.2 | 502 | 196 | 215 | 51 | 224 | 22 | 348 | 27 | 2,320 | 12 | 6.01 | 3.72 | 1.62 | 0.85 | 15.6 | 9.7 | 1.34 | .272 | 3.57 | 81 | 4.06 | 102 | 8.34 | -5.1 | |
| 8 | M. Buehrle | 390 | 161 | 119 | .575 | 365 | 3.83 | 1,396 | 27 | 8 | 0 | 2476.2 | 2,610 | 1,053 | 1,171 | 274 | 564 | 55 | 6 | 39 | 10,317 | 21 | 5.07 | 2.05 | 2.48 | 1.00 | 13.5 | 5.5 | 1.28 | .291 | 4.26 | 84 | 4.13 | 90 | 9.48 | 123.3 | |
| 9 | H. Wilhelm | 361 | 41 | 33 | .554 | 3 | 1.92 | 521 | 0 | 0 | 99 | 675.2 | 465 | 144 | 178 | 38 | 167 | 15 | 239 | 20 | 2,636 | 23 | 6.94 | 2.22 | 3.12 | 0.51 | 19.8 | 6.3 | 0.94 | .225 | 2.37 | 58 | 2.51 | 74 | 6.19 | 66.9 | |
| 10 | D. White | 360 | 159 | 123 | .564 | 301 | 2.30 | 1,067 | 206 | 42 | 4 | 2498.1 | 2,220 | 638 | 870 | 28 | 542 | 93 | 48 | 9,872 | 49 | 3.84 | 1.95 | 1.97 | 0.10 | 10.8 | 5.5 | 1.11 | .269 | 3.13 | 88 | 2.50 | 98 | 8.00 | -4.7 | ||
| 11 | E. Cicotte | 353 | 156 | 101 | .607 | 258 | 2.25 | 961 | 183 | 28 | 21 | 2322.1 | 2,050 | 581 | 764 | 23 | 533 | 22 | 69 | 9,059 | 26 | 3.72 | 2.07 | 1.80 | 0.09 | 10.6 | 5.9 | 1.11 | .270 | 2.96 | 75 | 2.48 | 83 | 7.94 | 130.7 | ||
| 12 | K. Foulke | 346 | 18 | 19 | .486 | 0 | 2.87 | 425 | 0 | 0 | 100 | 446.0 | 339 | 142 | 148 | 43 | 103 | 19 | 216 | 13 | 1,773 | 7 | 8.58 | 2.08 | 4.13 | 0.87 | 24.0 | 5.8 | 0.99 | .250 | 2.99 | 61 | 3.25 | 69 | 6.84 | 70.8 | |
| 13 | R. Hernandez | 345 | 29 | 24 | .547 | 3 | 2.87 | 411 | 0 | 0 | 161 | 404.2 | 339 | 129 | 146 | 32 | 156 | 9 | 299 | 16 | 1,696 | 15 | 9.14 | 3.47 | 2.63 | 0.71 | 24.2 | 9.2 | 1.22 | .282 | 3.25 | 66 | 3.25 | 74 | 7.54 | 53.5 | |
| 14 | B. Jenks | 329 | 14 | 18 | .438 | 0 | 3.40 | 334 | 0 | 0 | 173 | 341.2 | 302 | 129 | 137 | 25 | 110 | 8 | 282 | 23 | 1,419 | 16 | 8.80 | 2.90 | 3.04 | 0.66 | 23.5 | 7.8 | 1.21 | .294 | 3.61 | 75 | 3.15 | 69 | 7.96 | 52.4 | |
| 15 | J. Horlen | 329 | 113 | 113 | .500 | 284 | 3.11 | 1,007 | 59 | 18 | 3 | 1918.0 | 1,755 | 663 | 750 | 142 | 534 | 49 | 25 | 61 | 7,895 | 64 | 4.73 | 2.51 | 1.89 | 0.67 | 12.8 | 6.8 | 1.19 | .262 | 3.52 | 89 | 3.35 | 95 | 8.24 | 41 | |
| 16 | J. Scott | 317 | 107 | 114 | .484 | 226 | 2.30 | 945 | 123 | 26 | 9 | 1892.0 | 1,624 | 483 | 686 | 21 | 609 | 53 | 63 | 7,487 | 32 | 4.50 | 2.90 | 1.55 | 0.10 | 12.6 | 8.1 | 1.18 | .274 | 3.26 | 85 | 2.63 | 96 | 7.73 | 21.2 | ||
| 17 | S. Radinsky | 316 | 24 | 16 | .600 | 0 | 3.62 | 201 | 0 | 0 | 32 | 275.2 | 261 | 111 | 124 | 18 | 129 | 6 | 104 | 15 | 1,208 | 5 | 6.56 | 4.21 | 1.56 | 0.59 | 16.6 | 10.7 | 1.41 | .285 | 4.05 | 89 | 3.74 | 91 | 8.52 | 10.2 | |
| 18 | B. Simas | 308 | 18 | 19 | .486 | 0 | 3.83 | 265 | 0 | 0 | 23 | 338.1 | 332 | 144 | 159 | 39 | 149 | 14 | 102 | 27 | 1,481 | 9 | 7.05 | 3.96 | 1.78 | 1.04 | 17.9 | 10.1 | 1.42 | .289 | 4.23 | 81 | 4.51 | 95 | 8.83 | 8.8 | |
| 19 | B. Howry | 294 | 13 | 17 | .433 | 0 | 3.74 | 286 | 0 | 0 | 49 | 322.1 | 279 | 134 | 143 | 39 | 133 | 16 | 138 | 18 | 1,359 | 14 | 7.99 | 3.71 | 2.15 | 1.09 | 21.0 | 9.8 | 1.28 | .271 | 3.99 | 80 | 4.26 | 91 | 7.79 | 16.1 | |
| 20 | A. Bummer | 289 | 14 | 15 | .483 | 0 | 3.84 | 309 | 0 | 0 | 5 | 272.0 | 226 | 116 | 132 | 18 | 129 | 16 | 35 | 9 | 1,161 | 23 | 10.22 | 4.27 | 2.40 | 0.60 | 26.6 | 11.1 | 1.31 | .302 | 4.37 | 89 | 3.37 | 76 | 7.48 | 31.9 | |
| 21 | E. Fisher | 286 | 46 | 34 | .575 | 49 | 3.33 | 404 | 6 | 2 | 44 | 762.0 | 680 | 282 | 313 | 71 | 212 | 12 | 137 | 16 | 3,131 | 27 | 4.77 | 2.50 | 1.91 | 0.84 | 12.9 | 6.8 | 1.17 | .250 | 3.70 | 93 | 3.59 | 99 | 8.03 | 3.6 | |
| 22 | N. Jones | 284 | 22 | 13 | .629 | 0 | 3.12 | 318 | 0 | 0 | 9 | 291.1 | 245 | 101 | 111 | 28 | 110 | 10 | 63 | 9 | 1,200 | 25 | 9.82 | 3.40 | 2.89 | 0.86 | 26.5 | 9.2 | 1.22 | .296 | 3.43 | 72 | 3.38 | 80 | 7.57 | 27.3 | |
| 23 | D. Marte | 279 | 14 | 12 | .538 | 0 | 2.78 | 281 | 0 | 0 | 31 | 259.0 | 195 | 80 | 84 | 23 | 119 | 13 | 86 | 16 | 1,070 | 8 | 9.76 | 4.14 | 2.36 | 0.80 | 26.3 | 11.1 | 1.21 | .271 | 2.92 | 60 | 3.52 | 76 | 6.78 | 31.4 | |
| 24 | B. Locker | 271 | 28 | 22 | .560 | 0 | 2.68 | 296 | 0 | 0 | 48 | 423.1 | 350 | 126 | 147 | 23 | 109 | 18 | 137 | 42 | 1,725 | 12 | 6.29 | 2.32 | 2.72 | 0.49 | 17.2 | 6.3 | 1.08 | .256 | 3.13 | 83 | 2.71 | 81 | 7.44 | 28.7 | |
| 25 | G. Staley | 270 | 38 | 25 | .603 | 10 | 2.61 | 210 | 5 | 0 | 38 | 541.2 | 496 | 157 | 189 | 44 | 126 | 9 | 146 | 32 | 2,200 | 10 | 3.49 | 2.09 | 1.67 | 0.73 | 9.5 | 5.7 | 1.15 | .250 | 3.14 | 68 | 3.51 | 91 | 8.24 | 20.6 | |