| NAME | SO | G | W | L | W% | GS | ERA | CG | SHO | SV | IP | H | ER | R | HR | BB | HBP | GF | IBB | TBF | WP | K/9 | BB/9 | K/BB | HR/9 | K% | BB% | WHIP | BABIP | RA | ERA- | FIP | FIP- | H/9 | PRAA | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | T. Skubal | 469 | 62 | 31 | 10 | .756 | 62 | 2.30 | 1 | 1 | 0 | 387.1 | 283 | 99 | 109 | 33 | 68 | 14 | 0 | 0 | 1,501 | 5 | 10.90 | 1.58 | 6.90 | 0.77 | 31.2 | 4.5 | 0.91 | .273 | 2.53 | 57 | 2.46 | 60 | 6.58 | 70.4 | |
| 2 | G. Crochet | 464 | 64 | 24 | 17 | .585 | 64 | 3.00 | 1 | 1 | 0 | 351.1 | 288 | 117 | 123 | 42 | 79 | 8 | 0 | 0 | 1,409 | 10 | 11.89 | 2.02 | 5.87 | 1.08 | 32.9 | 5.6 | 1.04 | .301 | 3.15 | 72 | 2.80 | 66 | 7.38 | 54.5 | |
| 3 | D. Cease | 439 | 65 | 22 | 23 | .489 | 65 | 3.98 | 1 | 1 | 0 | 357.1 | 289 | 158 | 171 | 39 | 136 | 7 | 0 | 2 | 1,484 | 17 | 11.06 | 3.43 | 3.23 | 0.98 | 29.6 | 9.2 | 1.19 | .290 | 4.31 | 99 | 3.31 | 82 | 7.28 | 29.7 | |
| 4 | Z. Wheeler | 419 | 56 | 26 | 12 | .684 | 56 | 2.63 | 1 | 0 | 0 | 349.2 | 246 | 102 | 110 | 39 | 85 | 16 | 0 | 0 | 1,372 | 10 | 10.78 | 2.19 | 4.93 | 1.00 | 30.5 | 6.2 | 0.95 | .255 | 2.83 | 63 | 3.07 | 74 | 6.33 | 42.4 | |
| 5 | S. Gray | 404 | 60 | 27 | 17 | .614 | 60 | 4.07 | 1 | 1 | 0 | 347.0 | 327 | 157 | 172 | 46 | 77 | 6 | 0 | 0 | 1,424 | 9 | 10.48 | 2.00 | 5.25 | 1.19 | 28.4 | 5.4 | 1.16 | .315 | 4.46 | 99 | 3.26 | 81 | 8.48 | 29.5 | |
| 6 | F. Peralta | 404 | 65 | 28 | 15 | .651 | 65 | 3.19 | 0 | 0 | 0 | 350.1 | 267 | 124 | 128 | 47 | 134 | 19 | 0 | 0 | 1,448 | 12 | 10.38 | 3.44 | 3.01 | 1.21 | 27.9 | 9.3 | 1.14 | .261 | 3.29 | 76 | 3.89 | 94 | 6.86 | 9.6 | |
| 7 | C. Rodón | 398 | 65 | 34 | 18 | .654 | 65 | 3.50 | 0 | 0 | 0 | 370.1 | 289 | 144 | 155 | 53 | 130 | 19 | 0 | 0 | 1,525 | 7 | 9.67 | 3.16 | 3.06 | 1.29 | 26.1 | 8.5 | 1.13 | .255 | 3.77 | 86 | 4.06 | 96 | 7.02 | 8.2 | |
| 8 | L. Webb | 396 | 67 | 28 | 21 | .571 | 67 | 3.34 | 1 | 1 | 0 | 411.2 | 412 | 153 | 165 | 25 | 96 | 8 | 0 | 3 | 1,697 | 6 | 8.66 | 2.10 | 4.13 | 0.55 | 23.3 | 5.7 | 1.23 | .330 | 3.61 | 83 | 2.77 | 70 | 9.01 | 54.7 | |
| 9 | L. Gilbert | 393 | 58 | 15 | 18 | .455 | 58 | 3.31 | 1 | 0 | 0 | 339.2 | 252 | 125 | 136 | 46 | 68 | 11 | 0 | 1 | 1,338 | 21 | 10.41 | 1.80 | 5.78 | 1.22 | 29.4 | 5.1 | 0.94 | .251 | 3.60 | 87 | 3.29 | 83 | 6.68 | 25.5 | |
| 10 | C. Sale | 390 | 50 | 25 | 8 | .758 | 49 | 2.46 | 0 | 0 | 0 | 303.1 | 243 | 83 | 86 | 20 | 71 | 19 | 0 | 0 | 1,212 | 7 | 11.57 | 2.11 | 5.49 | 0.59 | 32.2 | 5.9 | 1.04 | .313 | 2.55 | 59 | 2.32 | 58 | 7.21 | 57.7 | |
| 11 | P. Skenes | 386 | 55 | 21 | 13 | .618 | 55 | 1.96 | 1 | 0 | 0 | 320.2 | 230 | 70 | 76 | 21 | 74 | 12 | 0 | 0 | 1,247 | 4 | 10.83 | 2.08 | 5.22 | 0.59 | 31.0 | 5.9 | 0.95 | .277 | 2.13 | 46 | 2.39 | 58 | 6.46 | 61 | |
| 12 | H. Brown | 385 | 62 | 23 | 18 | .561 | 61 | 2.94 | 1 | 0 | 0 | 355.1 | 289 | 116 | 126 | 35 | 117 | 12 | 0 | 1 | 1,441 | 4 | 9.75 | 2.96 | 3.29 | 0.89 | 26.7 | 8.1 | 1.14 | .285 | 3.19 | 73 | 3.35 | 82 | 7.32 | 29.5 | |
| 13 | J. Flaherty | 382 | 59 | 21 | 22 | .488 | 59 | 3.90 | 0 | 0 | 0 | 323.0 | 282 | 140 | 146 | 47 | 97 | 9 | 0 | 1 | 1,330 | 10 | 10.64 | 2.70 | 3.94 | 1.31 | 28.7 | 7.3 | 1.17 | .296 | 4.07 | 97 | 3.65 | 89 | 7.86 | 16.2 | |
| 14 | Y. Kikuchi | 380 | 65 | 16 | 21 | .432 | 65 | 4.02 | 0 | 0 | 0 | 354.0 | 347 | 158 | 172 | 49 | 118 | 5 | 0 | 3 | 1,508 | 12 | 9.66 | 3.00 | 3.22 | 1.25 | 25.2 | 7.8 | 1.31 | .312 | 4.37 | 99 | 3.84 | 92 | 8.82 | 13.9 | |
| 15 | M. Gore | 366 | 62 | 15 | 27 | .357 | 62 | 4.03 | 0 | 0 | 0 | 326.0 | 323 | 146 | 168 | 35 | 129 | 16 | 0 | 0 | 1,411 | 26 | 10.10 | 3.56 | 2.84 | 0.97 | 25.9 | 9.1 | 1.39 | .333 | 4.64 | 98 | 3.63 | 88 | 8.92 | 18.3 | |
| 16 | C. Sánchez | 365 | 63 | 24 | 14 | .632 | 63 | 2.89 | 3 | 1 | 0 | 383.2 | 353 | 123 | 134 | 23 | 88 | 6 | 0 | 0 | 1,561 | 13 | 8.56 | 2.06 | 4.15 | 0.54 | 23.4 | 5.6 | 1.15 | .306 | 3.14 | 69 | 2.75 | 66 | 8.28 | 59.8 | |
| 17 | N. Pivetta | 362 | 58 | 19 | 17 | .528 | 57 | 3.44 | 0 | 0 | 0 | 327.1 | 257 | 125 | 133 | 50 | 86 | 4 | 0 | 2 | 1,316 | 5 | 9.95 | 2.36 | 4.21 | 1.37 | 27.5 | 6.5 | 1.05 | .254 | 3.66 | 83 | 3.74 | 91 | 7.07 | 13.4 | |
| 18 | F. Valdez | 356 | 59 | 28 | 18 | .609 | 59 | 3.30 | 3 | 0 | 0 | 368.1 | 311 | 135 | 142 | 28 | 123 | 13 | 0 | 0 | 1,505 | 20 | 8.70 | 3.01 | 2.89 | 0.68 | 23.7 | 8.2 | 1.18 | .287 | 3.47 | 82 | 3.31 | 81 | 7.60 | 32.2 | |
| 19 | M. Fried | 355 | 61 | 30 | 15 | .667 | 61 | 3.04 | 2 | 1 | 0 | 369.2 | 310 | 125 | 144 | 27 | 108 | 17 | 0 | 0 | 1,515 | 14 | 8.64 | 2.63 | 3.29 | 0.66 | 23.4 | 7.1 | 1.13 | .281 | 3.51 | 74 | 3.19 | 77 | 7.55 | 38.9 | |
| 20 | K. Gausman | 351 | 63 | 24 | 22 | .522 | 63 | 3.71 | 3 | 2 | 0 | 374.0 | 320 | 154 | 165 | 41 | 106 | 5 | 0 | 2 | 1,531 | 4 | 8.45 | 2.55 | 3.31 | 0.99 | 22.9 | 6.9 | 1.14 | .271 | 3.97 | 92 | 3.58 | 87 | 7.70 | 22.8 | |
| 21 | T. Bibee | 349 | 62 | 24 | 19 | .558 | 62 | 3.87 | 2 | 1 | 0 | 356.0 | 320 | 153 | 163 | 49 | 98 | 18 | 0 | 1 | 1,472 | 5 | 8.82 | 2.48 | 3.56 | 1.24 | 23.7 | 6.7 | 1.17 | .283 | 4.12 | 96 | 3.95 | 97 | 8.09 | 5.4 | |
| 22 | J. Ryan | 341 | 54 | 20 | 17 | .541 | 53 | 3.50 | 0 | 0 | 0 | 306.0 | 248 | 119 | 128 | 45 | 62 | 17 | 0 | 0 | 1,227 | 2 | 10.03 | 1.82 | 5.50 | 1.32 | 27.8 | 5.1 | 1.01 | .266 | 3.76 | 86 | 3.60 | 87 | 7.29 | 18.2 | |
| 23 | L. Castillo | 337 | 62 | 22 | 20 | .524 | 62 | 3.59 | 0 | 0 | 0 | 356.0 | 326 | 142 | 149 | 48 | 93 | 12 | 0 | 2 | 1,464 | 3 | 8.52 | 2.35 | 3.62 | 1.21 | 23.0 | 6.4 | 1.18 | .285 | 3.77 | 94 | 3.89 | 98 | 8.24 | 2.5 | |
| 24 | C. Bassitt | 334 | 63 | 21 | 23 | .477 | 62 | 4.06 | 1 | 0 | 0 | 341.1 | 354 | 154 | 171 | 40 | 122 | 29 | 0 | 2 | 1,494 | 6 | 8.81 | 3.22 | 2.74 | 1.05 | 22.4 | 8.2 | 1.39 | .324 | 4.51 | 101 | 4.04 | 98 | 9.33 | 3.5 | |
| 25 | B. Singer | 333 | 64 | 23 | 25 | .479 | 64 | 3.86 | 0 | 0 | 0 | 349.1 | 325 | 150 | 157 | 41 | 114 | 24 | 0 | 0 | 1,478 | 5 | 8.58 | 2.94 | 2.92 | 1.06 | 22.5 | 7.7 | 1.26 | .294 | 4.04 | 89 | 3.95 | 93 | 8.37 | 10.8 | |