| NAME | GG | W | L | W% | G | GS | ERA | SO | CG | SHO | SV | IP | H | ER | R | HR | BB | HBP | GF | IBB | TBF | WP | K/9 | BB/9 | K/BB | HR/9 | K% | BB% | WHIP | BABIP | RA | ERA- | FIP | FIP- | H/9 | PRAA | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | B. Gibson | 9 | 251 | 174 | .591 | 528 | 482 | 2.91 | 3,117 | 255 | 56 | 6 | 3884.1 | 3,279 | 1,258 | 1,420 | 257 | 1,336 | 102 | 21 | 118 | 16,068 | 108 | 7.22 | 3.10 | 2.33 | 0.60 | 19.4 | 8.3 | 1.19 | .268 | 3.29 | 78 | 2.89 | 81 | 7.60 | 290.5 | |
| 2 | J. Kaat | 16 | 283 | 237 | .544 | 898 | 625 | 3.45 | 2,461 | 180 | 31 | 17 | 4530.1 | 4,620 | 1,738 | 2,038 | 395 | 1,083 | 122 | 102 | 116 | 19,023 | 128 | 4.89 | 2.15 | 2.27 | 0.78 | 12.9 | 5.7 | 1.26 | .282 | 4.05 | 93 | 3.41 | 91 | 9.18 | 165.8 | |
| 3 | P. Niekro | 5 | 318 | 274 | .537 | 864 | 716 | 3.35 | 3,342 | 245 | 45 | 29 | 5404.0 | 5,044 | 2,012 | 2,337 | 482 | 1,809 | 123 | 83 | 86 | 22,677 | 226 | 5.57 | 3.01 | 1.85 | 0.80 | 14.7 | 8.0 | 1.27 | .270 | 3.89 | 87 | 3.61 | 95 | 8.40 | 116.1 | |
| 4 | S. Carlton | 1 | 329 | 244 | .574 | 741 | 709 | 3.22 | 4,136 | 254 | 55 | 2 | 5217.2 | 4,672 | 1,864 | 2,130 | 414 | 1,833 | 53 | 13 | 150 | 21,683 | 183 | 7.13 | 3.16 | 2.26 | 0.71 | 19.1 | 8.5 | 1.25 | .279 | 3.67 | 87 | 3.14 | 86 | 8.06 | 271.5 | |
| 5 | J. Palmer | 4 | 268 | 152 | .638 | 558 | 521 | 2.86 | 2,212 | 211 | 53 | 4 | 3948.0 | 3,349 | 1,253 | 1,395 | 303 | 1,311 | 38 | 15 | 37 | 16,114 | 85 | 5.04 | 2.99 | 1.69 | 0.69 | 13.7 | 8.1 | 1.18 | .249 | 3.18 | 80 | 3.50 | 95 | 7.63 | 83.2 | |
| 6 | R. Reuschel | 2 | 214 | 191 | .528 | 557 | 529 | 3.37 | 2,015 | 102 | 26 | 5 | 3548.1 | 3,588 | 1,330 | 1,494 | 221 | 935 | 88 | 16 | 117 | 14,888 | 89 | 5.11 | 2.37 | 2.16 | 0.56 | 13.5 | 6.3 | 1.27 | .290 | 3.79 | 89 | 3.21 | 85 | 9.10 | 225.7 | |
| 7 | O. Hershiser | 1 | 204 | 150 | .576 | 510 | 466 | 3.48 | 2,014 | 68 | 25 | 5 | 3130.1 | 2,939 | 1,211 | 1,366 | 235 | 1,007 | 117 | 19 | 108 | 13,150 | 121 | 5.79 | 2.90 | 2.00 | 0.68 | 15.3 | 7.7 | 1.26 | .277 | 3.93 | 89 | 3.68 | 93 | 8.45 | 84.8 | |
| 8 | G. Maddux | 18 | 355 | 227 | .610 | 744 | 740 | 3.16 | 3,371 | 109 | 35 | 0 | 5008.1 | 4,726 | 1,756 | 1,981 | 353 | 999 | 137 | 3 | 177 | 20,421 | 70 | 6.06 | 1.80 | 3.37 | 0.63 | 16.5 | 4.9 | 1.14 | .281 | 3.56 | 76 | 3.25 | 78 | 8.49 | 519.5 | |
| 9 | K. Rogers | 5 | 219 | 156 | .584 | 762 | 474 | 4.27 | 1,968 | 36 | 9 | 28 | 3302.2 | 3,457 | 1,568 | 1,739 | 339 | 1,175 | 127 | 133 | 53 | 14,280 | 79 | 5.36 | 3.20 | 1.67 | 0.92 | 13.8 | 8.2 | 1.40 | .292 | 4.74 | 93 | 4.38 | 97 | 9.42 | 43.3 | |
| 10 | M. Mussina | 7 | 270 | 153 | .638 | 537 | 536 | 3.68 | 2,813 | 57 | 23 | 0 | 3562.2 | 3,460 | 1,458 | 1,559 | 376 | 785 | 60 | 0 | 29 | 14,593 | 71 | 7.11 | 1.98 | 3.58 | 0.95 | 19.3 | 5.4 | 1.19 | .292 | 3.94 | 82 | 3.57 | 79 | 8.74 | 372.8 | |
| 11 | M. Buehrle | 4 | 214 | 160 | .572 | 518 | 493 | 3.81 | 1,870 | 33 | 10 | 0 | 3283.1 | 3,472 | 1,391 | 1,542 | 361 | 734 | 79 | 6 | 49 | 13,705 | 27 | 5.13 | 2.01 | 2.55 | 0.99 | 13.6 | 5.4 | 1.28 | .292 | 4.23 | 87 | 4.11 | 93 | 9.52 | 111.9 | |
| 12 | Z. Greinke | 6 | 225 | 156 | .591 | 586 | 541 | 3.49 | 2,979 | 17 | 5 | 1 | 3389.1 | 3,207 | 1,315 | 1,410 | 367 | 762 | 79 | 8 | 25 | 13,877 | 101 | 7.91 | 2.02 | 3.91 | 0.97 | 21.5 | 5.5 | 1.17 | .293 | 3.74 | 83 | 3.51 | 85 | 8.52 | 235 | |
| 13 | A. Wainwright | 2 | 200 | 128 | .610 | 478 | 411 | 3.53 | 2,202 | 28 | 11 | 3 | 2668.1 | 2,577 | 1,047 | 1,117 | 233 | 736 | 81 | 13 | 40 | 11,116 | 51 | 7.43 | 2.48 | 2.99 | 0.79 | 19.8 | 6.6 | 1.24 | .298 | 3.77 | 88 | 3.53 | 87 | 8.69 | 152.8 | |
| 14 | C. Kershaw | 1 | 223 | 96 | .699 | 455 | 451 | 2.53 | 3,052 | 25 | 15 | 0 | 2855.1 | 2,193 | 804 | 881 | 235 | 713 | 46 | 1 | 28 | 11,279 | 108 | 9.62 | 2.25 | 4.28 | 0.74 | 27.1 | 6.3 | 1.02 | .271 | 2.78 | 65 | 2.85 | 70 | 6.91 | 375.1 |