Between the 2000 and 2009 seasons, Tim Wakefield fanned the most hitters for the Red Sox, with 1,209 strikeouts.

	NAME	SO	G	W	L	W%	GS	ERA	CG	SHO	SV	IP	H	ER	R	HR	BB	HBP	GF	IBB	TBF	WP	K/9	BB/9	K/BB	HR/9	K%	BB%	WHIP	BABIP	RA	ERA-	FIP	FIP-	H/9	PRAA
1	Tim Wakefield T. Wakefield	1,209	346	110	95	.537	250	4.33	7	0	7	1747.0	1,664	840	928	224	616	107	30	18	7,477	71	6.23	3.17	1.96	1.15	16.2	8.2	1.31	.271	4.78	93	4.60	106	8.57	-55.8
2	Pedro Martinez P. Martinez	1,119	139	75	26	.743	139	2.53	14	5	0	936.2	696	263	290	68	205	60	0	1	3,712	15	10.75	1.97	5.46	0.65	30.1	5.5	0.96	.278	2.79	54	2.44	56	6.69	208.3
3	Josh Beckett J. Beckett	723	122	65	34	.657	122	4.05	6	2	0	792.0	751	356	375	96	203	31	0	3	3,299	22	8.22	2.31	3.56	1.09	21.9	6.2	1.20	.292	4.26	87	3.78	87	8.53	47.4
4	Curt Schilling C. Schilling	574	119	53	29	.646	98	3.95	4	1	9	675.0	712	296	301	84	108	13	21	2	2,795	5	7.65	1.44	5.31	1.12	20.5	3.9	1.21	.312	4.01	85	3.56	82	9.49	60.3
5	Derek Lowe D. Lowe	503	239	61	41	.598	101	3.83	2	1	66	788.2	799	336	382	57	242	38	114	20	3,362	17	5.74	2.76	2.08	0.65	15.0	7.2	1.32	.294	4.36	82	3.75	86	9.12	53.7
6	Jon Lester J. Lester	487	92	42	16	.724	91	3.66	4	2	0	558.0	540	227	234	51	204	19	0	2	2,359	15	7.85	3.29	2.39	0.82	20.6	8.6	1.33	.306	3.77	79	3.77	88	8.71	32.2
7	Daisuke Matsuzaka D. Matsuzaka	409	73	37	21	.638	73	4.00	1	0	0	431.2	400	192	196	47	204	22	0	3	1,873	18	8.53	4.25	2.00	0.98	21.8	10.9	1.40	.296	4.09	87	4.26	100	8.34	-0.5
8	Jonathan Papelbon J. Papelbon	346	268	14	11	.560	3	1.84	0	0	151	298.0	215	61	70	21	77	12	227	5	1,187	5	10.45	2.33	4.49	0.63	29.1	6.5	0.98	.265	2.11	40	2.62	61	6.49	56.8
9	Mike Timlin M. Timlin	273	394	30	22	.577	0	3.76	0	0	27	409.0	422	171	183	44	98	17	119	22	1,730	8	6.01	2.16	2.79	0.97	15.8	5.7	1.27	.291	4.03	81	3.99	92	9.29	15
10	Bronson Arroyo B. Arroyo	256	73	24	19	.558	61	4.19	0	0	1	401.1	394	187	220	39	105	35	3	8	1,708	10	5.74	2.35	2.44	0.87	15.0	6.1	1.24	.279	4.93	91	4.06	94	8.84	11
11	John Burkett J. Burkett	231	61	25	17	.595	59	4.85	2	1	0	354.2	401	191	201	45	97	17	1	6	1,545	5	5.86	2.46	2.38	1.14	15.0	6.3	1.40	.308	5.10	106	4.30	100	10.18	-0.4
12	Hideo Nomo H. Nomo	220	33	13	10	.565	33	4.50	2	2	0	198.0	171	99	105	26	96	3	0	2	849	6	10.00	4.36	2.29	1.18	25.9	11.3	1.35	.288	4.77	99	4.03	94	7.77	5.7
13	Manny Delcarmen M. Delcarmen	211	241	8	4	.667	0	3.74	0	0	3	240.1	223	100	108	16	103	12	40	7	1,045	1	7.90	3.86	2.05	0.60	20.2	9.9	1.36	.294	4.04	81	3.68	86	8.35	16.7
14	Frank Castillo F. Castillo	201	64	16	24	.400	49	4.66	0	0	1	301.0	313	156	173	33	94	12	4	8	1,295	4	6.01	2.81	2.14	0.99	15.5	7.3	1.35	.293	5.17	102	4.14	97	9.36	3.7
15	Casey Fossum C. Fossum	190	75	14	11	.560	33	4.42	0	0	2	230.0	239	113	137	25	84	14	18	1	1,004	8	7.43	3.29	2.26	0.98	18.9	8.4	1.40	.310	5.36	97	4.03	94	9.35	6.5
16	Matt Clement M. Clement	189	44	18	11	.621	44	5.09	1	0	0	256.1	269	145	152	26	106	22	0	1	1,140	16	6.64	3.72	1.78	0.91	16.6	9.3	1.46	.305	5.34	111	4.38	102	9.44	-3.2
17	Hideki Okajima H. Okajima	176	198	12	4	.750	0	2.72	0	0	6	192.0	155	58	58	20	61	4	30	6	788	2	8.25	2.86	2.89	0.94	22.3	7.7	1.13	.256	2.72	59	3.69	86	7.27	12.6
18	Rolando Arrojo R. Arrojo	173	83	14	9	.609	30	4.39	0	0	6	256.0	238	125	132	25	84	22	15	5	1,087	7	6.08	2.95	2.06	0.88	15.9	7.7	1.26	.272	4.64	94	4.20	96	8.37	4.5
19	Clay Buchholz C. Buchholz	162	36	12	14	.462	34	4.91	2	1	0	190.2	198	104	113	24	87	5	0	2	844	3	7.65	4.11	1.86	1.13	19.2	10.3	1.49	.307	5.33	107	4.50	106	9.35	-5.4
20	Alan Embree A. Embree	155	211	8	9	.471	0	4.69	0	0	4	178.1	164	93	99	24	49	3	44	7	734	1	7.82	2.47	3.16	1.21	21.1	6.7	1.19	.278	5.00	102	3.90	90	8.28	8.4
21	Keith Foulke K. Foulke	149	159	13	9	.591	0	3.73	0	0	47	178.1	168	74	76	25	40	13	114	6	748	5	7.52	2.02	3.73	1.26	19.9	5.3	1.17	.274	3.84	81	4.10	94	8.48	5
22	Julian Tavarez J. Tavarez	139	101	12	16	.429	29	4.94	1	0	1	246.0	279	135	155	24	104	14	15	7	1,099	7	5.09	3.80	1.34	0.88	12.6	9.5	1.56	.312	5.67	106	4.76	110	10.21	-12.1
23	Rich Garces R. Garces	136	152	14	3	.824	0	4.09	0	0	2	163.0	140	74	80	17	60	8	21	8	690	5	7.51	3.31	2.27	0.94	19.7	8.7	1.23	.262	4.42	87	4.01	91	7.73	7.9
24	Justin Masterson J. Masterson	135	67	9	8	.529	15	3.76	0	0	0	160.1	140	67	69	17	65	14	10	5	677	4	7.58	3.65	2.08	0.95	19.9	9.6	1.28	.276	3.87	82	4.28	101	7.86	-0.8
25	David Wells D. Wells	131	38	17	10	.630	38	4.56	2	0	0	231.0	284	117	125	31	29	9	0	0	986	4	5.10	1.13	4.52	1.21	13.3	2.9	1.35	.322	4.87	100	4.14	97	11.06	3.2