Answered January 12th, 2020

Since 1950, Terry Forster has the most strikeouts - home runs allowed * walks allowed with 100.0+ innings pitched in a season, with 104 in 1972.

most k-(hr*bb) in a season 100 ip since 1950
Interpreted as:
most k-(hr*bb) by a player in a season 100 or more ip since 1950

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