Answered January 12th, 2020

Since 1950, Clayton Kershaw has the most strikeouts - home runs allowed * walks allowed / 100 when pitching at least 1000 innings, with 1,465.79.

most k-(hr*bb/100) in a career 1000 ip since 1950
Interpreted as:
most k-(hr*bb/100) by a player in a career 1000 or more ip since 1950

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