best performing stocks from 10/6/2025 to 12/05/2025 with a market cap over 1 billion

Praxis Precision Medicines  (PRAX) had the highest return between October 6, 2025 and December 5, 2025 by a US stock with a market cap of $1B+, returning 354%.

ASSETDATE% RETURN
Praxis Precision Medicines  (PRAX)
10/6/2025 - 12/5/2025
354.03%
Capricor Therapeutics (CAPR)
10/6/2025 - 12/5/2025
269.37%
Terns Pharmaceuticals (TERN)
10/6/2025 - 12/5/2025
243.79%
Guild Holdings  (GHLD)
10/6/2025 - 12/5/2025
231.75%
Cogent Biosciences (COGT)
10/6/2025 - 12/5/2025
145.22%
Olema Pharmaceuticals (OLMA)
10/6/2025 - 12/5/2025
141.87%
Nuvation Bio (NUVB)
10/6/2025 - 12/5/2025
126.19%
Hotel101 Global Holdings Corp Class A Ordinary Shares (HBNB)
10/6/2025 - 12/5/2025
123.73%
PACS (PACS)
10/6/2025 - 12/5/2025
122.58%
Monte Rosa Therapeutics (GLUE)
10/6/2025 - 12/5/2025
122.35%
Grupo Supervielle (SUPV)
10/6/2025 - 12/5/2025
116.73%
Central Puerto (CEPU)
10/6/2025 - 12/5/2025
116.18%
Cidara Therapeutics (CDTX)
10/6/2025 - 12/5/2025
112.72%
Empresa Distribuidora y Comercializadora Norte SA ADR (EDN)
10/6/2025 - 12/5/2025
109.17%
Celcuity LLC (CELC)
10/6/2025 - 12/5/2025
109.13%
Spyre Therapeutics (SYRE)
10/6/2025 - 12/5/2025
108.67%
Banco Macro SA B ADR (BMA)
10/6/2025 - 12/5/2025
101.67%
BBVA Banco Frances SA ADR (BBAR)
10/6/2025 - 12/5/2025
97.54%
Belite Bio Inc ADR (BLTE)
10/6/2025 - 12/5/2025
97.5%
Lumentum (LITE)
10/6/2025 - 12/5/2025
96.1%
ProPetro (PUMP)
10/6/2025 - 12/5/2025
94.47%
Vicor (VICR)
10/6/2025 - 12/5/2025
93.82%
Apogee Therapeutics, Inc Common Stock (APGE)
10/6/2025 - 12/5/2025
92.65%
Nurix Therapeutics  (NRIX)
10/6/2025 - 12/5/2025
91.63%
MBX Biosciences, Inc Common Stock (MBX)
10/6/2025 - 12/5/2025
90.24%