Wilt Chamberlain had the most games with 45+ points, with 176 games.

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most nba games 45 points
Interpreted as:
most NBA regular-season games by a player 45 or more points
ChamberlainJordanBryantBaylorHardenIversonBarryCurryGervinWilkinsJamesWestWestbrookAbdul-JabbarBirdKingPettitDantleyMcAdooLillardDurantMcGradyArchibaldAnthonyRobertson176764641403231252423222120201918181717161615151414
NAMEGPPTSMPGPPGRPGAPGSPGBPGTPGFGMFGAFG%3PM3PA3P%FTMFTAFT%MINREBASTSTLBLKTOVPF+/-
Wilt ChamberlainWilt Chamberlain1769,48453.926.021.940.054.710.117.059.24,573316
Michael JordanMichael Jordan763,77641.749.76.84.92.91.23.018.531.159.50.82.039.711.913.587.73,17251737422188229227+136
Kobe BryantKobe Bryant462,34743.751.06.23.81.70.62.817.533.352.53.77.946.012.414.386.22,0102851747928131128+417
Elgin BaylorElgin Baylor412,04850.018.512.916.279.4153
James HardenJames Harden402,04840.351.27.37.52.30.65.115.028.452.86.313.745.914.916.689.91,6122933009024205121+449
Allen IversonAllen Iverson321,55645.548.64.46.02.50.24.116.732.451.62.35.642.112.815.483.51,45614019281513083+115
Rick BarryRick Barry311,53643.149.58.55.02.63.318.936.551.811.712.991.21,3362631562910101
Stephen CurryStephen Curry251,23436.749.45.05.41.60.33.516.027.059.19.716.359.37.88.393.39161261344078755+309
George GervinGeorge Gervin241,15840.248.35.22.91.41.018.631.459.40.20.923.510.812.388.196512470342360
Dominique WilkinsDominique Wilkins231,11841.948.67.73.12.00.63.317.630.857.11.22.352.812.314.186.89631787146147746
LeBron JamesLeBron James221,10243.150.17.86.92.00.93.417.128.759.74.78.554.811.113.880.994817215143197447+164
Jerry WestJerry West211,01048.117.929.760.412.315.082.2
Russell WestbrookRussell Westbrook2096639.448.39.78.12.00.34.816.532.450.93.69.039.711.813.885.57881931623959554+58
Kareem Abdul-JabbarKareem Abdul-Jabbar2098849.415.34.20.31.86.019.831.662.50.00.09.913.573.630583176
Larry BirdLarry Bird1992043.148.410.96.21.90.93.918.831.160.61.23.139.09.510.491.981820811836177546
Bernard KingBernard King1887841.248.88.23.71.60.33.618.329.861.60.10.428.612.015.278.8742148662866454
Bob PettitBob Pettit1887848.818.232.955.212.415.083.063
Adrian DantleyAdrian Dantley1782342.648.46.94.20.116.523.969.00.00.10.015.518.085.972411871155
Bob McAdooBob McAdoo1781447.916.65.019.329.365.99.311.680.22835
Damian LillardDamian Lillard1683439.452.14.48.11.40.32.516.027.957.47.814.055.412.413.194.3631711292344024+165
Kevin DurantKevin Durant1677543.848.48.64.31.61.13.215.628.355.04.38.550.713.014.391.27021386925175138+32
Tracy McGradyTracy McGrady1573142.248.78.35.41.71.13.117.230.756.14.38.849.210.013.573.96331248125174636+120
Nate ArchibaldNate Archibald1572248.13.417.730.557.912.814.886.551
Carmelo AnthonyCarmelo Anthony1466941.047.87.92.41.00.52.117.428.361.43.35.956.19.811.187.8574111341473050+79
Oscar RobertsonOscar Robertson1467147.910.49.616.115.817.789.114613441