Hakeem Olajuwon had the most games with 5+ blocks, with 281 games.

most games with 5 blks
Interpreted as:
most regular-season games by a player with 5 or more blks
OlajuwonMutomboEatonRobinsonBolEwingBradleyMourningCambyRatliffO'NealDuncanWallaceIbakaO'NealHowardBenjaminNanceDavisKirilenkoSmithBrandDalembertFoyleRollins281234232214184170160155154135132124101828278736965626160595656
NAMEGPBLKMPGPPGRPGAPGSPGBPGTPGFGMFGAFG%3PM3PA3P%FTMFTAFT%MINPTSREBASTSTLTOVPF+/-
Hakeem OlajuwonHakeem Olajuwon2811,77839.324.513.02.72.06.33.29.618.851.20.00.122.65.37.372.411,0486,8983,6577575658981,061+230
Dikembe MutomboDikembe Mutombo2341,47838.313.413.41.40.66.32.34.89.153.10.00.00.03.85.766.48,9663,1393,124318130537728+793
Mark EatonMark Eaton2321,53233.87.910.01.30.56.61.93.06.745.30.00.01.82.766.27,8471,8282,329292121438846
David RobinsonDavid Robinson2141,33138.124.811.82.91.76.22.98.816.453.80.00.125.87.19.773.38,1625,3142,532624358614644+315
Manute BolManute Bol1841,21326.13.76.10.40.36.60.91.63.742.20.10.419.70.51.051.44,8016781,1246563165565
Patrick EwingPatrick Ewing17098038.625.411.72.31.25.83.29.818.951.90.00.121.15.77.575.86,5634,3161,988386202548626+164
Shawn BradleyShawn Bradley16099031.611.19.31.00.86.21.84.49.944.80.00.111.12.23.171.95,0501,7701,488156124285583+551
Alonzo MourningAlonzo Mourning15592736.020.810.21.40.66.03.17.513.854.50.00.121.45.78.368.95,5733,2311,58721191474552+672
Marcus CambyMarcus Camby15492535.211.112.12.51.16.01.74.59.746.80.00.122.22.02.967.55,4131,7031,859378171262451+647
Theo RatliffTheo Ratliff13579133.710.77.90.80.65.91.74.18.050.60.00.00.02.63.671.74,5481,4411,07010686226428+591
Shaquille O'NealShaquille O'Neal13275038.927.113.53.10.75.72.910.718.857.20.00.00.05.610.454.25,1413,5791,78040994389494+625
Tim DuncanTim Duncan12468437.721.913.33.30.85.52.98.316.450.80.00.129.45.27.569.84,6732,7171,64340696357311+1067
Ben WallaceBen Wallace10157938.58.713.51.71.85.71.33.57.050.50.00.10.01.63.347.03,8898741,366169186128209+649
Serge IbakaSerge Ibaka8248931.912.78.50.60.56.01.25.410.253.50.30.935.21.52.075.42,6141,0437005337100228+525
Jermaine O'NealJermaine O'Neal8246637.419.511.02.10.65.72.57.615.848.10.00.120.04.26.069.93,0661,59690317648201272+349
Dwight HowardDwight Howard7844138.119.114.21.70.95.73.36.611.657.10.00.120.05.810.057.72,9701,4891,10513168255240+572
Benoit BenjaminBenoit Benjamin7344238.516.611.22.81.06.13.36.612.851.40.00.10.03.54.871.42,8121,21481520874244242
Larry NanceLarry Nance6940537.719.59.23.11.05.91.97.814.354.50.00.116.73.95.079.22,6041,34863221672129171
Anthony DavisAnthony Davis6537737.225.011.12.71.55.82.19.218.250.80.51.535.75.97.677.72,4181,62372217399134138+259
Andrei KirilenkoAndrei Kirilenko6236236.916.17.43.71.85.82.75.210.848.50.61.834.85.06.873.72,286998457230109167142+480
Josh SmithJosh Smith6134336.816.38.63.81.75.62.86.013.544.70.51.830.83.75.171.02,246992522230101172162+53
Elton BrandElton Brand6033139.321.010.12.60.95.52.68.115.054.20.00.0100.04.76.572.62,3601,25860315554153192+135
Samuel DalembertSamuel Dalembert5932734.510.210.40.80.65.51.84.37.755.00.00.01.72.373.92,0346046115038109201+43
Adonal FoyleAdonal Foyle5631927.97.38.40.80.65.71.43.36.948.10.00.00.61.542.41,564406471433176161+35
Tree RollinsTree Rollins5632931.28.18.70.80.75.91.23.56.454.90.00.01.11.668.51,748455487463766196
StatMuse has game-level data for blocks going back to the 1983-84 season.