The Carolina Panthers have a record of 54-54-1 against the AFC all-time.

carolina panthers record vs. the afc
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TEAMGPRECW%WLTTDPTSPPGOPP PTSOPP PPG1DWN3DWN%4DWN%
Carolina PanthersCarolina Panthers10954-54-1.500545412402,19220.12,36821.72,00538.052.5