The Arizona Cardinals had the highest point differential by a team in a game in 2015, with a 40-point differential versus the 49ers on September 27, 2015.
Interpreted as:
highest point differential by a team in a regular-season game in 2015| TEAM | DIFF | DATE | TM | OPP | RESULT | TD | 1DWN | OFF | OPP OFF | 3DWN% | 4DWN% | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | Cardinals | 40 | 9/27/2015 | vs | W 47-7 | 6 | 28 | 446 | 156 | 46.2 | 100.0 | ||
| 2 |  | Panthers | 38 | 12/13/2015 | vs | W 38-0 | 5 | 20 | 424 | 230 | 50.0 | 0.0 | ||
| 3 |  | Jaguars | 35 | 12/13/2015 | vs | W 51-16 | 7 | 24 | 380 | 322 | 22.2 | 100.0 | ||
| 4 |  | Steelers | 35 | 12/6/2015 | vs | W 45-10 | 5 | 24 | 522 | 240 | 61.5 | |||
| 5 |  | Chiefs | 35 | 11/1/2015 | vs | W 45-10 | 6 | 24 | 340 | 276 | 61.5 | |||
| 6 |  | Bengals | 34 | 12/6/2015 | @ | W 37-3 | 4 | 20 | 377 | 273 | 41.7 | 66.7 | ||
| 7 |  | Patriots | 34 | 9/27/2015 | vs | W 51-17 | 6 | 35 | 471 | 293 | 78.6 | |||
| 8 |  | Redskins | 33 | 11/15/2015 | vs | W 47-14 | 5 | 23 | 510 | 350 | 54.5 | |||
| 9 |  | Vikings | 32 | 12/27/2015 | vs | W 49-17 | 5 | 17 | 368 | 363 | 37.5 | |||
| 10 |  | Seahawks | 31 | 12/6/2015 | @ | W 38-7 | 5 | 25 | 433 | 125 | 69.2 | 100.0 | ||
| 11 |  | Lions | 31 | 11/26/2015 | vs | W 45-14 | 6 | 28 | 430 | 227 | 50.0 | |||
| 12 | | Seahawks | 30 | 1/3/2016 | @ | W 36-6 | 4 | 22 | 354 | 232 | 53.3 | 100.0 | ||
| 13 | | Cardinals | 30 | 12/27/2015 | vs | W 38-8 | 5 | 19 | 381 | 178 | 50.0 | |||
| 14 | | Chiefs | 30 | 11/22/2015 | @ | W 33-3 | 4 | 22 | 385 | 201 | 41.7 | 100.0 | ||
| 15 | | Seahawks | 29 | 12/13/2015 | @ | W 35-6 | 5 | 28 | 424 | 302 | 66.7 | |||
| 16 | | Patriots | 29 | 10/29/2015 | vs | W 36-7 | 4 | 24 | 437 | 270 | 25.0 | 100.0 | ||
| 17 | | Panthers | 28 | 1/3/2016 | vs | W 38-10 | 5 | 23 | 366 | 386 | 70.0 | |||
| 18 |  | Texans | 28 | 12/27/2015 | @ | W 34-6 | 4 | 19 | 330 | 257 | 43.8 | |||
| 19 | | Panthers | 28 | 11/22/2015 | vs | W 44-16 | 5 | 27 | 368 | 186 | 50.0 | 0.0 | ||
| 20 |  | Buccaneers | 28 | 11/22/2015 | @ | W 45-17 | 6 | 25 | 521 | 383 | 62.5 | 100.0 | ||
| 21 |  | Dolphins | 28 | 10/18/2015 | @ | W 38-10 | 5 | 26 | 434 | 299 | 55.6 | |||
| 22 |  | Titans | 28 | 9/13/2015 | @ | W 42-14 | 6 | 20 | 309 | 273 | 44.4 | |||
| 23 |  | Falcons | 27 | 10/4/2015 | vs | W 48-21 | 7 | 22 | 378 | 428 | 56.3 | 100.0 | ||
| 24 |  | Bills | 27 | 9/27/2015 | @ | W 41-14 | 5 | 21 | 428 | 391 | 53.8 | |||
| 25 | | Seahawks | 26 | 9/27/2015 | vs | W 26-0 | 2 | 17 | 371 | 146 | 31.3 | 100.0 | ||
WAS
CHIMore NFL News
Cavaliers seek more from Evan Mobley as East finals shift to Cleveland for Game 3
NFL MVP Matthew Stafford agrees to 1-year contract extension with Rams through 2027
Bears reiterate Chicago stadium options are 'exhausted,' focused on suburban Illinois and Indiana
Robert Saleh says Cam Ward’s shoulder is 'perfectly healthy' as Titans install new offense
Lions sign All-Pro linebacker Jack Campbell to 4-year contract extension
Jaxson Dart says he's 'not like Tim Tebow,' but the Giants QB has worked to get leaner
More Cardinals Stats
Team Leaders 
PASS
3,366
Brissett
RUSH
333
Carter
REC
1,239
McBride
Team Rankings
PPG
20.9
23rd
OPP PPG
28.7
29th
RUSH YDS/G
93.1
31st
PASS YDS/G
256.1
5th
NFL 2025 Leaders
NFL 2025 Rankings
NFL Fantasy 2025
NFL 2025 Betting
NFL 2025 Standings
| AFC East | W | L | T | PCT |
|---|---|---|---|---|
 Patriots - y | 14 | 3 | 0 | .824 |
 Bills - w | 12 | 5 | 0 | .706 |
 Dolphins - e | 7 | 10 | 0 | .412 |
 Jets - e | 3 | 14 | 0 | .176 |
| AFC North | W | L | T | PCT |
 Steelers - y | 10 | 7 | 0 | .588 |
 Ravens - e | 8 | 9 | 0 | .471 |
 Bengals - e | 6 | 11 | 0 | .353 |
 Browns - e | 5 | 12 | 0 | .294 |
| AFC South | W | L | T | PCT |
 Jaguars - y | 13 | 4 | 0 | .765 |
 Texans - w | 12 | 5 | 0 | .706 |
 Colts - e | 8 | 9 | 0 | .471 |
 Titans - e | 3 | 14 | 0 | .176 |
| AFC West | W | L | T | PCT |
 Broncos - z* | 14 | 3 | 0 | .824 |
 Chargers - w | 11 | 6 | 0 | .647 |
 Chiefs - e | 6 | 11 | 0 | .353 |
 Raiders - e | 3 | 14 | 0 | .176 |
| NFC East | W | L | T | PCT |
|---|---|---|---|---|
 Eagles - y | 11 | 6 | 0 | .647 |
 Cowboys - e | 7 | 9 | 1 | .441 |
 Commanders - e | 5 | 12 | 0 | .294 |
 Giants - e | 4 | 13 | 0 | .235 |
| NFC North | W | L | T | PCT |
 Bears - y | 11 | 6 | 0 | .647 |
 Packers - w | 9 | 7 | 1 | .559 |
 Vikings - e | 9 | 8 | 0 | .529 |
 Lions - e | 9 | 8 | 0 | .529 |
| NFC South | W | L | T | PCT |
 Panthers - y | 8 | 9 | 0 | .471 |
 Buccaneers - e | 8 | 9 | 0 | .471 |
 Falcons - e | 8 | 9 | 0 | .471 |
 Saints - e | 6 | 11 | 0 | .353 |
| NFC West | W | L | T | PCT |
 Seahawks - z* | 14 | 3 | 0 | .824 |
 Rams - w | 12 | 5 | 0 | .706 |
 49ers - w | 12 | 5 | 0 | .706 |
 Cardinals - e | 3 | 14 | 0 | .176 |