Matthew Stafford has thrown the most career interceptions by an active quarterback, with 192 interceptions.
| NAME | INT | GP | CMP | ATT | PCT | YDS | AVG | YDS/G | TD | RTG | TD% | INT% | SCK | SCKY | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | M. Stafford | 192 | 234 | 5,440 | 8,567 | 63.5 | 62,882 | 7.3 | 268.7 | 409 | 92.2 | 4.8 | 2.2 | 519 | 3,479 |
| 2 |  | J. Flacco | 172 | 206 | 4,413 | 7,161 | 61.6 | 48,148 | 6.7 | 233.7 | 272 | 84.1 | 3.8 | 2.4 | 422 | 3,000 |
| 3 |  | A. Dalton | 151 | 179 | 3,539 | 5,651 | 62.6 | 39,793 | 7.0 | 222.3 | 254 | 87.5 | 4.5 | 2.7 | 363 | 2,372 |
| 4 |  | K. Cousins | 127 | 169 | 3,837 | 5,738 | 66.9 | 43,662 | 7.6 | 258.4 | 291 | 97.2 | 5.1 | 2.2 | 338 | 2,443 |
| 5 |  | A. Rodgers | 123 | 259 | 5,571 | 8,555 | 65.1 | 65,038 | 7.6 | 251.1 | 522 | 102.4 | 6.1 | 1.4 | 591 | 4,038 |
| 6 |  | R. Wilson | 114 | 205 | 3,951 | 6,120 | 64.6 | 46,966 | 7.7 | 229.1 | 353 | 99.3 | 5.8 | 1.9 | 570 | 3,749 |
| 7 |  | J. Winston | 113 | 107 | 1,981 | 3,242 | 61.1 | 24,792 | 7.6 | 231.7 | 156 | 86.4 | 4.8 | 3.5 | 222 | 1,383 |
| 8 |  | J. Goff | 99 | 147 | 3,336 | 5,058 | 66.0 | 38,392 | 7.6 | 261.2 | 248 | 96.9 | 4.9 | 2.0 | 275 | 1,995 |
| 9 |  | B. Mayfield | 95 | 118 | 2,400 | 3,782 | 63.5 | 27,432 | 7.3 | 232.5 | 190 | 91.5 | 5.0 | 2.5 | 274 | 1,751 |
| 10 |  | J. Allen | 94 | 123 | 2,539 | 3,978 | 63.8 | 29,266 | 7.4 | 237.9 | 214 | 94.0 | 5.4 | 2.4 | 217 | 1,332 |
| 11 |  | D. Prescott | 92 | 135 | 3,114 | 4,643 | 67.1 | 35,074 | 7.6 | 259.8 | 239 | 98.4 | 5.1 | 2.0 | 278 | 1,684 |
| 12 |  | G. Smith | 86 | 106 | 1,974 | 3,031 | 65.1 | 21,675 | 7.2 | 204.5 | 120 | 87.5 | 4.0 | 2.8 | 268 | 1,924 |
| 13 |  | P. Mahomes | 81 | 124 | 3,063 | 4,612 | 66.4 | 35,590 | 7.7 | 287.0 | 267 | 101.6 | 5.8 | 1.8 | 211 | 1,379 |
| 14 |  | S. Darnold | 78 | 95 | 1,664 | 2,680 | 62.1 | 19,296 | 7.2 | 203.1 | 117 | 86.3 | 4.4 | 2.9 | 212 | 1,408 |
| 15 |  | C. Wentz | 72 | 103 | 2,195 | 3,496 | 62.8 | 23,626 | 6.8 | 229.4 | 159 | 89.1 | 4.5 | 2.1 | 262 | 1,680 |
| 16 |  | M. Mariota | 61 | 101 | 1,481 | 2,352 | 63.0 | 17,543 | 7.5 | 173.7 | 106 | 89.9 | 4.5 | 2.6 | 201 | 1,308 |
| 17 |  | K. Murray | 60 | 87 | 1,974 | 2,941 | 67.1 | 20,460 | 7.0 | 235.2 | 121 | 92.2 | 4.1 | 2.0 | 195 | 1,413 |
| 18 |  | T. Tagovailoa | 58 | 76 | 1,612 | 2,372 | 68.0 | 17,786 | 7.5 | 234.0 | 117 | 96.2 | 4.9 | 2.4 | 136 | 932 |
| 19 |  | T. Lawrence | 57 | 72 | 1,524 | 2,429 | 62.7 | 16,451 | 6.8 | 228.5 | 85 | 84.5 | 3.5 | 2.3 | 144 | 989 |
| 20 |  | J. Herbert | 55 | 91 | 2,210 | 3,322 | 66.5 | 23,935 | 7.2 | 263.0 | 158 | 96.5 | 4.8 | 1.7 | 209 | 1,339 |
| 21 |  | D. Jones | 54 | 82 | 1,693 | 2,618 | 64.7 | 17,623 | 6.7 | 214.9 | 89 | 86.8 | 3.4 | 2.1 | 230 | 1,481 |
| 22 |  | L. Jackson | 53 | 112 | 1,825 | 2,813 | 64.9 | 21,900 | 7.8 | 195.5 | 181 | 102.2 | 6.4 | 1.9 | 219 | 1,193 |
| 23 |  | J. Garoppolo | 52 | 83 | 1,304 | 1,936 | 67.4 | 15,828 | 8.2 | 190.7 | 96 | 97.6 | 5.0 | 2.7 | 140 | 936 |
| 24 |  | C. Keenum | 51 | 80 | 1,392 | 2,233 | 62.3 | 15,175 | 6.8 | 189.7 | 79 | 84.6 | 3.5 | 2.3 | 131 | 989 |
| 25 |  | M. Jones | 50 | 62 | 1,236 | 1,859 | 66.5 | 12,741 | 6.9 | 205.5 | 67 | 86.9 | 3.6 | 2.7 | 114 | 807 |
StatMuse has season-level data for intercepted passes going back to the 1932 season.
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