5 players were tied for the most total touchdowns in a game in 2006, with 4 touchdowns. The first three are Steven Jackson on December 31, 2006, Reggie Bush on December 3, 2006 and Joseph Addai on November 26, 2006.

most tds by one player in a game in the 2006 nfl season
Interpreted as:
most tds by one player in a regular-season game in the 2006 NFL season
12/31/2006Jackson12/3/2006Bush11/26/2006Addai11/19/2006Tomlinson11/12/2006Tomlinson10/29/2006Johnson10/15/2006Tomlinson12/31/2006Johnson12/30/2006Barber12/18/2006Harrison12/10/2006Karney12/10/2006Pinner12/10/2006Jones-Drew12/10/2006Tomlinson12/3/2006Dillon12/3/2006Shipp11/19/2006Johnson11/19/2006Lewis11/5/2006Walker11/5/2006Tomlinson10/29/2006Wayne10/29/2006Tomlinson4444444333333333333333

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