Derrick Henry got the most total touchdowns in a game in 2018, with 4 touchdowns versus the Jaguars on December 6, 2018.

most tds by one player in a game in the 2018 nfl season
Interpreted as:
most tds by one player in a regular-season game in the 2018 NFL season
12/6/2018Henry12/30/2018Jarwin12/13/2018Williams12/9/2018Cooper11/18/2018Barkley11/11/2018Ebron11/8/2018McCaffrey11/4/2018Hunt11/4/2018Kamara10/21/2018Gurley10/21/2018Hunt10/14/2018Gordon10/14/2018Hill10/7/2018Gurley9/30/2018Kamara9/23/2018Ridley9/16/2018Gordon9/16/2018Gurley9/13/2018Green9/9/2018Kamara9/9/2018Hill12/30/2018Jones4333333333333333333332

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