8 quarterbacks are tied for the most passing touchdowns by a quarterback in a game, with 7 touchdowns. The first three are Drew Brees on November 1, 2015, Nick Foles on November 3, 2013 and Peyton Manning on September 5, 2013.

most touchdowns in a game by a quarterback
Interpreted as:
most passing touchdowns in a regular-season game by a quarterback

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