23 teams are tied for the most wins with a point differential of 50 or above in a season, with 1 win. The first three are the St. Louis Rams in 2014 and in 1976, the Seattle Seahawks in 2012 and the New Orleans Saints in 2011.

most wins by 50 points or more by a nfl team in a season
Interpreted as:
most wins by 50 or higher points or more by a NFL team in a season

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