The San Francisco 49ers are 4-1-1 against the spread versus the Texans between November 2, 2005 and November 2, 2025.
| TEAM | DATE | ATS | TM | OPP | RESULT | SPREAD | ATS DIFF | O/U | O/U DIFF | TD | 1DWN | OFF | OPP OFF | 3DWN% | 4DWN% | |||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | 49ers | 1/1/2006 | 1-0 |  SF | vs |  HOU | W 20-17 | +1 | +4 (Y) | 37.5 | -0.5 (U) | 2 | 19 | 324 | 284 | 36.8 | |||
| 2 | | 49ers | 10/25/2009 | 0-0-1 | SF | +160 | @ | HOU | -185 | L 21-24 | +3 | 0 (P) | 44.5 | +0.5 (O) | 3 | 17 | 297 | 336 | 36.4 | 0.0 |
| 3 | | 49ers | 10/6/2013 | 1-0 | SF | -215 | vs | HOU | +185 | W 34-3 | -4 | +27 (Y) | 43 | -6 (U) | 4 | 17 | 284 | 313 | 36.4 | 0.0 |
| 4 | | 49ers | 12/10/2017 | 1-0 | SF | +108 | @ | HOU | -118 | W 26-16 | -1.5 | +8.5 (Y) | 45.5 | -3.5 (U) | 2 | 20 | 416 | 311 | 18.2 | |
| 5 | | 49ers | 1/2/2022 | 1-0 | SF | -740 | vs | HOU | +507 | W 23-7 | -13.5 | +2.5 (Y) | 44.5 | -14.5 (U) | 2 | 19 | 416 | 222 | 38.5 | 0.0 |
| 6 | | 49ers | 10/26/2025 | 0-1 | SF | +135 | @ | HOU | -159 | L 15-26 | +3 | -8 (N) | 42 | -1 (U) | 2 | 12 | 223 | 475 | 33.3 | 0.0 |
| Average | 12.5 | 2.5 | 17.3 | 326.7 | 323.5 | 33.8 | 0.0 | |||||||||||||
| Total | 4-1-1 | 15 | 104 | 1,960 | 1,941 | 33.8 | 0.0 |
StatMuse has team, game-level data for spread records going back to the 1979 season.
More 49ers Stats
Team Rankings
PPG
20.0
25th
OPP PPG
20.5
8th
RUSH YDS/G
89.4
30th
PASS YDS/G
272.9
2nd
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