Randy Moss has the most receiving touchdowns in a game against the Bills, with 4 touchdowns on November 18, 2007.

what is the most receiving tds against the bills in a game by one player regular season or playoffs
11/18/2007Moss9/23/2001Harrison11/26/1995Coates9/23/1984Walker12/18/1966Scarpitto11/15/1964Cappelletti9/28/1963Hennigan10/22/1961Lott11/27/1960Taylor1/24/2021Kelce10/19/2020Kelce10/13/2020Smith10/21/2018Hilton9/16/2018Gordon11/19/2017Allen10/22/2017Howard11/7/2016Graham12/20/2015Reed9/27/2015Matthews9/20/2015Edelman10/12/2014LaFell9/21/2014Royal4333333332222222222222
NAMEDATEGAME TYPETMOPPREC TDRECTRGREC YDSREC AVGRUSH YDSATTRUSH AVGRUSH TD
Randy MossRandy Moss11/18/2007REGNENE@ BUF
@
4101312812.8000
Marvin HarrisonMarvin Harrison9/23/2001REGINDINDvs. BUF
vs.
371214620.9000
Ben CoatesBen Coates11/26/1995REGNENE@ BUF
@
366010.0000
Wesley WalkerWesley Walker9/23/1984REGNYJNYJ@ BUF
@
3712818.3000
Bob ScarpittoBob Scarpitto12/18/1966REGDENDEN@ BUF
@
3512324.6000
Gino CappellettiGino Cappelletti11/15/1964REGBOSBOS@ BUF
@
349022.5000
Charley HenniganCharley Hennigan9/28/1963REGHOUHOU@ BUF
@
3812315.4000
Billy LottBilly Lott10/22/1961REGBOSBOSvs. BUF
vs.
3610818.051105.10
Lionel TaylorLionel Taylor11/27/1960REGDENDENvs. BUF
vs.
3919922.1000
Travis KelceTravis Kelce1/24/2021PSTKCKCvs. BUF
vs.
213151189.1000
Travis KelceTravis Kelce10/19/2020REGKCKC@ BUF
@
2576513.0000
Jonnu SmithJonnu Smith10/13/2020REGTENTENvs. BUF
vs.
257408.0000
T.Y. HiltonT.Y. Hilton10/21/2018REGINDINDvs. BUF
vs.
244256.3000
Melvin GordonMelvin Gordon9/16/2018REGLACLAC@ BUF
@
267386.32893.11
Keenan AllenKeenan Allen11/19/2017REGLACLACvs. BUF
vs.
2121315913.3313.00
O.J. HowardO.J. Howard10/22/2017REGTBTB@ BUF
@
2669816.3000
Jimmy GrahamJimmy Graham11/7/2016REGSEASEAvs. BUF
vs.
28810312.9000
Jordan ReedJordan Reed12/20/2015REGWASWASvs. BUF
vs.
2778412.0000
Rishard MatthewsRishard Matthews9/27/2015REGMIAMIAvs. BUF
vs.
261011318.8000
Julian EdelmanJulian Edelman9/20/2015REGNENE@ BUF
@
21119978.812112.00
Brandon LaFellBrandon LaFell10/12/2014REGNENE@ BUF
@
2469724.3000
Eddie RoyalEddie Royal9/21/2014REGSDSD@ BUF
@
2464210.5000
Jimmy GrahamJimmy Graham10/27/2013REGNONOvs. BUF
vs.
2333712.3000
Kenny StillsKenny Stills10/27/2013REGNONOvs. BUF
vs.
23412943.0414.00
Brandon GibsonBrandon Gibson10/20/2013REGMIAMIAvs. BUF
vs.
258408.0000
Results may be incomplete. StatMuse has complete game-level data for receiving touchdowns going back to the 1960 season.

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