Since 1980, the New England Patriots have the most wins by a team, with 393 wins.

which nfl team has the most wins since 1980
Interpreted as:
Which NFL team has the most regular-season wins since 1980?
PatriotsSteelersBroncosPackers49ersCowboysEaglesChiefsDolphinsVikingsSeahawksSaintsBearsColtsGiantsBillsTitansChargersWashingtonRaidersRamsFalconsJets393390377375373359352351349347344337333331330326326319317309304300289
TEAMGPWLTTDPTSPPGOPP PTSOPP PPG1DWN3DWN%4DWN%
New England PatriotsNew England Patriots65539326201,75415,31423.412,80019.513,210
Pittsburgh SteelersPittsburgh Steelers65439026221,60514,35021.912,29518.812,555
Denver BroncosDenver Broncos65537727711,69014,92522.813,59720.813,205
Green Bay PackersGreen Bay Packers65637527651,80415,41523.513,72120.912,995
San Francisco 49ersSan Francisco 49ers65437327921,76915,24323.313,27120.312,841
Dallas CowboysDallas Cowboys65435929501,67514,62422.413,47120.612,886
Philadelphia EaglesPhiladelphia Eagles65535229851,64014,35621.913,21320.212,623
Kansas City ChiefsKansas City Chiefs65535130221,66214,60322.313,62820.812,637
Miami DolphinsMiami Dolphins65534930511,59713,94721.313,69420.912,474
Minnesota VikingsMinnesota Vikings65434730521,70214,77022.614,02021.412,757
Seattle SeahawksSeattle Seahawks65534431011,63514,21521.713,51020.612,263
New Orleans SaintsNew Orleans Saints65433731701,71314,82922.714,41422.012,780
Chicago BearsChicago Bears65533332201,47013,05119.913,00919.911,875
Indianapolis ColtsIndianapolis Colts65533132311,60314,13521.614,75422.512,801
New York GiantsNew York Giants65533032321,49813,40820.513,54720.712,253
Buffalo BillsBuffalo Bills65432632801,52413,45120.613,67820.912,256
Tennessee TitansTennessee Titans65532632901,58013,93521.314,37822.012,278
Los Angeles ChargersLos Angeles Chargers65431933501,70214,75322.614,36122.013,039
Washington Football TeamWashington Football Team65531733621,55413,75221.014,01121.412,414
Las Vegas RaidersLas Vegas Raiders65530934601,53813,55420.714,77222.611,977
Los Angeles RamsLos Angeles Rams65530435011,60214,01421.414,84122.712,264
Atlanta FalconsAtlanta Falcons65430035221,59214,10921.615,11523.112,571
New York JetsNew York Jets65428936321,43612,88119.714,01421.412,042
Cincinnati BengalsCincinnati Bengals65528736441,57213,68220.914,84322.712,542
Arizona CardinalsArizona Cardinals65627238041,45912,79319.515,24823.212,171
Tampa Bay BuccaneersTampa Bay Buccaneers65526738711,42312,58219.214,36321.911,781
Detroit LionsDetroit Lions65525939421,49313,40420.515,19823.212,059
Cleveland BrownsCleveland Browns60723836721,25011,14618.413,17721.710,706
Baltimore RavensBaltimore Ravens40723017619849,12222.47,71519.07,74038.550.4
Carolina PanthersCarolina Panthers42320321919948,94421.19,11621.67,88137.848.0
Jacksonville JaguarsJacksonville Jaguars42217824409448,46820.19,29122.07,89537.948.7
Houston TexansHouston Texans31113617507196,48920.97,19923.15,94538.152.1