Drew Brees has played the most seasons with 4,500+ passing yards, with 8 seasons.

who has the most seasons with 4500 passing yards
Interpreted as:
Who has the most seasons with 4500 or more passing yards?
BreesRyanBradyManningRiversStaffordGoffMahomesLuckRoethlisbergerWarnerMoonMarinoFoutsWatsonAllenWinstonPrescottCousinsPalmerRomoManningRodgers87665322222222111111111
NAMEGPSEASYDSCMPATTPCTAVGYDS/GTDTD%INTINT%SCKSCKYRATE
Drew BreesDrew Brees127840,5343,5525,22967.97.8319.22975.71272.42121,47499.8
Matt RyanMatt Ryan112732,9682,8854,27667.57.7294.42064.8862.02531,70798.1
Tom BradyTom Brady96628,8482,3883,64165.67.9300.52316.3551.51741,052104.6
Peyton ManningPeyton Manning96628,6202,4243,58667.68.0298.12466.9792.295641105.4
Philip RiversPhilip Rivers80523,2561,9102,95064.77.9290.71374.6762.61601,03193.6
Matthew StaffordMatthew Stafford48314,6551,2272,02460.67.2305.3904.4522.68863786.9
Jared GoffJared Goff3229,3267581,18763.97.9291.4544.5282.45539393.4
Patrick MahomesPatrick Mahomes3129,8377731,16866.28.4317.3887.5181.548318111.0
Andrew LuckAndrew Luck3229,3548101,25564.57.5292.3796.3312.54529597.6
Ben RoethlisbergerBen Roethlisberger32210,0818601,28367.07.9315.0665.1251.95733899.7
Kurt WarnerKurt Warner3229,4137761,14467.88.2294.2665.8363.16441599.0
Warren MoonWarren Moon3129,3797661,23961.87.6302.5564.5342.75942688.8
Dan MarinoDan Marino3229,8307401,18762.38.3307.2927.8403.430239100.3
Dan FoutsDan Fouts3229,5177081,19859.17.9297.4635.3413.45134487.7
Deshaun WatsonDeshaun Watson1614,82338254470.28.9301.4336.171.349293112.4
Josh AllenJosh Allen1614,54439657269.27.9284.0376.5101.726159107.2
Jameis WinstonJameis Winston1615,10938062660.78.2319.3335.3304.84728284.3
Dak PrescottDak Prescott1614,90238859665.18.2306.4305.0111.82315199.7
Kirk CousinsKirk Cousins1614,91740660667.08.1307.3254.1122.02319097.2
Carson PalmerCarson Palmer1614,67134253763.78.7291.9356.5112.025151104.6
Tony RomoTony Romo1614,90342564865.67.6306.4284.3192.93626390.5
Eli ManningEli Manning1614,93335958961.08.4308.3294.9162.72819992.9
Aaron RodgersAaron Rodgers1514,64334350268.39.2309.5459.061.236219122.5
Matt SchaubMatt Schaub1614,77039658367.98.2298.1295.0152.62514998.6
Jay CutlerJay Cutler1614,52638461662.37.3282.9254.1182.9116986.0
StatMuse has season-level data for passing yards going back to the 1932 season.

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