London Fletcher has made the most career tackles, with 1,200 tackles.

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who has the most tkl in a career safety
FletcherDavidBarberWagnerSmithAdamsKuechlyLaurinaitisSuggsHarrisonCampbellPollardBarronFooteReedKnightAllenWilsonBabineauxColeHaliLevyAbraham1.2k849847797763708690664624573555553541541534517503488471467460459445
NAMEGPTKLSFTYASTCOMBSCKSCKYINTINT YDSINT TDFFFRFR TD
London FletcherLondon Fletcher2081,20016051,80530.520619135219121
Lavonte DavidLavonte David14684913471,19625.017012169225171
Ronde BarberRonde Barber19284711651,01218.511041750713113
Bobby WagnerBobby Wagner14679715441,34123.5156101841693
Daryl SmithDaryl Smith19076313241,08730.5204128211371
Mike AdamsMike Adams22870812279356.03830337213160
Luke KuechlyLuke Kuechly11869014021,09212.573181531791
James LaurinaitisJames Laurinaitis117664120787116.5120.510740290
Terrell SuggsTerrell Suggs2446241262886139.09957144239151
James HarrisonJames Harrison193573122079384.5536.589503491
Calais CampbellCalais Campbell208555220576092.5645.5324014123
Bernard PollardBernard Pollard126553115971210.5641218011381
Mark BarronMark Barron119541116971012.071.59520540
Larry FooteLarry Foote187541126280325.0172.542601090
Ed ReedEd Reed17453411126466.056641,590711132
Sammy KnightSammy Knight12151711666837.0502535001291
Jared AllenJared Allen1875034145648136.0851.5655131191
Gibril WilsonGibril Wilson10048811376258.540131170870
Jordan BabineauxJordan Babineaux13147111296004.034.5122732841
Trent ColeTrent Cole176467114961690.5706.511912130
Tamba HaliTamba Hali177460113659689.5591.52113281
DeAndre LevyDeAndre Levy9545911796383.533121412250
John AbrahamJohn Abraham186445193538129.08481604661
Danieal ManningDanieal Manning12843511165514.026112171960
Jason Pierre-PaulJason Pierre-Paul162434116259691.5615.5467221101
StatMuse has season-level data for tackles going back to the 2001 season.