Night Train Lane has the most interceptions in a season, with 14 interceptions in his rookie season in 1952.

who holds the record for most interceptions in a season in the nfl
Interpreted as:
Who holds the record for most defensive interceptions in a season in the NFL?
1952Lane1980Hayes1950Sanders1948Sandifer1979Reinfeldt1974Thomas1964Krause1964Paulson1963Glick1953Christiansen1950Doll1950Lewis1949Nussbaumer1981Walls1975Blount1971Bradley1964Hall1962Riley1960Gonsoulin1958Patton1956Crow1955Sherman1953Keane1413131312121212121212121211111111111111111111
StatMuse has season-level data for interceptions going back to the 1940 season.

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