The San Francisco 49ers are 15-29 against the NFC at home since 2014.

49ers all-time home record vs nfc since 2014
TEAMGPRECW%WLTTDPTSPPGOPP PTSOPP PPG1DWN3DWN%4DWN%
San Francisco 49ersSan Francisco 49ers4415-29.341152909989420.31,02623.386838.342.3