The San Francisco 49ers have a record of 34-32-1 against the Bears all-time.

49ers vs bears all-time record including playoff
TEAMGPRECW%WLTTDPTSPPGOPP PTSOPP PPG1DWN3DWN%4DWN%
San Francisco 49ersSan Francisco 49ers6734-32-1.515343211801,49022.21,32119.71,220