The Buffalo Bills are 6-3 against the spread as favorites against the NFC on the road since January 26, 2020.
| TEAM | DATE | ATS | TM | OPP | RESULT | SPREAD | ATS DIFF | O/U | O/U DIFF | TD | 1DWN | OFF | OPP OFF | 3DWN% | 4DWN% | |||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | Bills | 11/25/2021 | 1-0 |  BUF | -302 | @ |  NO | +239 | W 31-6 | -7 | +18 (Y) | 45 | -8 (U) | 4 | 21 | 361 | 190 | 61.5 | 100.0 |
| 2 | | Bills | 9/8/2022 | 1-0 | BUF | -131 | @ |  LAR | +110 | W 31-10 | -2.5 | +18.5 (Y) | 52 | -11 (U) | 4 | 23 | 413 | 243 | 90.0 | |
| 3 | | Bills | 11/24/2022 | 0-1 | BUF | -433 | @ |  DET | +338 | W 28-25 | -9.5 | -6.5 (N) | 54.5 | -1.5 (U) | 3 | 28 | 401 | 326 | 58.3 | |
| 4 | | Bills | 12/24/2022 | 1-0 | BUF | -398 | @ |  CHI | +312 | W 35-13 | -8 | +14 (Y) | 40.5 | +7.5 (O) | 5 | 20 | 426 | 209 | 54.5 | 100.0 |
| 5 | | Bills | 9/24/2023 | 1-0 | BUF | -235 | @ |  WAS | +194 | W 37-3 | -5 | +29 (Y) | 44 | -4 (U) | 4 | 20 | 386 | 230 | 60.0 | 0.0 |
| 6 | | Bills | 10/27/2024 | 1-0 | BUF | -163 | @ |  SEA | +137 | W 31-10 | -3 | +18 (Y) | 45.5 | -4.5 (U) | 4 | 29 | 445 | 233 | 53.3 | 100.0 |
| 7 | | Bills | 12/8/2024 | 0-1 | BUF | -191 | @ | LAR | +158 | L 42-44 | -3.5 | -5.5 (N) | 50 | +36 (O) | 6 | 25 | 445 | 457 | 55.6 | |
| 8 | | Bills | 10/13/2025 | 0-1 | BUF | -203 | @ |  ATL | +169 | L 14-24 | -3.5 | -13.5 (N) | 49.5 | -11.5 (U) | 2 | 17 | 291 | 443 | 22.2 | 0.0 |
| 9 | | Bills | 10/26/2025 | 1-0 | BUF | -398 | @ |  CAR | +314 | W 40-9 | -7.5 | +23.5 (Y) | 47.5 | +1.5 (O) | 5 | 23 | 410 | 244 | 58.3 | |
| Average | 7.4 | 4.1 | 22.9 | 397.6 | 286.1 | 57.5 | 12.0 | |||||||||||||
| Total | 6-3 | 37 | 206 | 3,578 | 2,575 | 57.5 | 60.0 |
StatMuse has team, game-level data for spread records going back to the 1979 season.
More Bills Stats
Team Rankings
PPG
29.6
4th
OPP PPG
20.9
9th
RUSH YDS/G
164.4
1st
PASS YDS/G
230.6
16th
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