Jimmy Garoppolo has a 19-8 record against the AFC in his career.

garoppolo all-time record vs afc including playoffs
NAMEGPRECW%CMPATTPCTYDSAVGYDS/GTDTD%INTINT%SCKSCKYRATE
Jimmy GaroppoloJimmy Garoppolo2719-8.70428041767.13,4168.2126.5215.0133.12818496.0