The Detroit Lions are 158-145-1 against the NFC at home all-time.

lions all-time home record vs nfc
TEAMGPRECW%WLTTDPTSPPGOPP PTSOPP PPG1DWN3DWN%4DWN%
Detroit LionsDetroit Lions304158-145-1.52115814517516,69422.06,40221.15,591