The Detroit Lions have a record of 41-32 in the month of October against the NFC at home all-time.

lions all-time home record vs nfc in oct
TEAMGPRECW%WLTTDPTSPPGOPP PTSOPP PPG1DWN3DWN%4DWN%
Detroit LionsDetroit Lions7341-32.562413201931,64022.51,65222.61,336