Answered February 23rd, 2020

Gale Sayers had his most passing touchdowns + rushing touchdowns + receiving touchdowns + punt-return touchdowns in a game versus the 49ers on December 12, 1965, with 6.

most passing tds + rushing tds + receiving td + punt ret tds by gale sayers in a game
Interpreted as:
most passing tds + rushing tds + receiving td + punt ret tds by Gale Sayers in a regular-season game

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