Daryle Lamonica had the best winning percentage by a quarterback when playing >100 games, winning 77.0 percent of the time.

quarterbacks with the highest win percentage of all-time over 100 games
LamonicaBradyStaubachManningMcMahonYoungWilsonStrockRoethlisbergerWhiteRodgersMontanaBradshawHostetlerStablerRutledgeConerlyDetmerElwayUnitasGrieseKellyTheismann.770.766.718.703.697.686.674.674.672.669.664.661.661.655.652.645.644.641.639.638.637.631.629
NAMEGPW%CMPATTPCTYDSAVGYDS/GTDTD%INTINT%SCKSCKYRATE
Daryle LamonicaDaryle Lamonica137.7701,2552,52849.618,7177.4136.61616.41345.373.4
Tom BradyTom Brady308.7666,98110,90164.081,4797.5264.56025.51941.85303,33397.6
Roger StaubachRoger Staubach131.7181,6852,95857.022,7007.7173.31535.21093.783.4
Peyton ManningPeyton Manning266.7036,1259,38065.371,9407.7270.55395.72512.73031,95396.5
Jim McMahonJim McMahon119.6971,4922,57358.018,1487.1152.51003.9903.52261,34478.2
Steve YoungSteve Young169.6862,6674,14964.333,1248.0196.02325.61072.63582,05596.8
Russell WilsonRussell Wilson149.6742,9104,46065.235,1427.9235.92776.2821.84072,664102.3
Don StrockDon Strock167.67444377956.95,3496.932.0455.8425.474.9
Ben RoethlisbergerBen Roethlisberger239.6725,2038,07364.461,8637.7258.84035.02052.55283,49793.8
Danny WhiteDanny White136.6691,7382,90159.921,6577.5159.21545.31294.482.3
Aaron RodgersAaron Rodgers204.6644,4366,80865.252,9557.8259.64276.3921.44843,273104.1
Joe MontanaJoe Montana192.6613,4095,39163.240,5517.5211.22735.11392.692.3
Terry BradshawTerry Bradshaw168.6612,0253,90151.927,9897.2166.62125.42105.470.9
Jeff HostetlerJeff Hostetler152.6551,3572,33858.016,4307.0108.1944.0713.02071,15980.5
Ken StablerKen Stabler184.6522,2703,79359.827,9387.4151.81945.12225.975.3
Jeff RutledgeJeff Rutledge117.64527452652.13,6286.931.0163.0295.561.4
Charlie ConerlyCharlie Conerly135.6441,1282,27349.615,8057.0117.11426.21376.068.1
Koy DetmerKoy Detmer103.64118435452.01,9445.518.9102.8144.0127761.2
John ElwayJohn Elway234.6394,1237,25056.951,4757.1220.03004.12263.15163,78579.9
Johnny UnitasJohnny Unitas210.6382,8305,18654.640,2397.8191.62905.62534.978.2
Bob GrieseBob Griese161.6371,9263,42956.225,0927.3155.91925.61725.077.1
Jim KellyJim Kelly160.6312,8744,77960.135,4677.4221.72375.01753.73232,42784.4
Joe TheismannJoe Theismann167.6292,0443,60256.725,2067.0150.91604.41383.877.4
Brett FavreBrett Favre302.6236,30010,16962.071,8387.1237.95085.03363.35253,48786.0
Elvis GrbacElvis Grbac105.6191,4462,44559.116,7746.9159.8994.0813.312990779.6