The Seattle Seahawks have a record of 28-17 versus the 49ers all-time.

seattle seahawks all-time record against the 49ers
TEAMGPRECW%WLTTDPTSPPGOPP PTSOPP PPG1DWN3DWN%4DWN%
Seattle SeahawksSeattle Seahawks4528-17.622281701331,09924.483218.5904