Mario Williams has the most sacks for the Bills in a game, with 4.5 sacks versus the Panthers on September 15, 2013.

who had the most defensive sacks for the buffalo bills in a + game, minimum of 2 + sacks
Interpreted as:
Who had the most defensive sacks for the buffalo bills in a + regular-season game, minimum of 2 + defensive sacks?

See Trending NFL Searches