Drew Brees had the most passing yards + passing yards for the Saints in a game in 2019, with 746 versus the Cardinals on October 27.

who had the most passing+ yards for the new orleans saints in a game last season, minimum of 300 passing+ yards
Interpreted as:
Who had the most passing+ passing yards for the new orleans saints in a regular-season game last season, minimum of 300 passing+ passing yards?

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