Larry Fitzgerald has been targeted the most career times, with 2,335 targets.

who has the most targets without a catch all-time
FitzgeraldGonzalezSmithJohnsonBoldinWittenWayneMarshallMossOwensHoltWardGatesMasonHarrisonBrownWhiteJohnsonJonesJohnsonMuhammadWelkerMoss2.3k1.9k1.7k1.7k1.7k1.7k1.7k1.7k1.6k1.6k1.6k1.5k1.5k1.4k1.4k1.4k1.4k1.4k1.3k1.3k1.3k1.3k1.3k
NAMEGPTRGRECREC YDSAVGREC YDS/GREC TDRUSH YDSATTYPCRUSH YDS/GRUSH TD
Larry FitzgeraldLarry Fitzgerald2632,3351,43217,49212.266.512168203.40.30
Tony GonzalezTony Gonzalez2381,8621,23314,13811.559.41071427.00.10
Steve Smith Sr.Steve Smith Sr.2191,7451,03114,73114.367.381387576.81.82
Andre JohnsonAndre Johnson1931,7431,06214,18513.473.57054232.30.30
Anquan BoldinAnquan Boldin2021,7391,07613,77912.868.282229425.51.11
Jason WittenJason Witten2711,7231,22813,04610.648.174000.00
Reggie WayneReggie Wayne2111,7121,07014,34513.468.082040.00.00
Brandon MarshallBrandon Marshall1791,65097012,35112.769.083118205.90.70
Randy MossRandy Moss2021,61691313,97915.369.2139155246.50.80
Terrell OwensTerrell Owens1711,60491613,38114.678.3127198355.71.22
Torry HoltTorry Holt1731,56192013,38214.577.47457115.20.30
Hines WardHines Ward2011,52498511,83712.058.985415567.42.11
Antonio GatesAntonio Gates2361,45895511,84112.450.2116000.00
Derrick MasonDerrick Mason1981,43990411,54212.858.3631081.30.10
Marvin HarrisonMarvin Harrison1461,43190612,10213.482.91072054.00.10
Antonio BrownAntonio Brown1441,38691512,16413.384.583128353.70.90
Roddy WhiteRoddy White1711,37680810,86313.463.5631992.10.10
Chad JohnsonChad Johnson1661,37276611,05914.466.667175247.31.10
Julio JonesJulio Jones1401,34986513,19715.394.360118196.20.80
Calvin JohnsonCalvin Johnson1351,31573111,61915.986.183167198.81.21
Muhsin MuhammadMuhsin Muhammad1641,3047409,77313.259.65565106.50.40
Wes WelkerWes Welker1751,2769039,92411.056.750151197.90.90
Santana MossSantana Moss1971,26873210,28314.052.266287515.61.50
DeAndre HopkinsDeAndre Hopkins1331,25578010,42913.478.4671243.00.10
Donald DriverDonald Driver2051,23374310,13713.649.461217346.41.11
StatMuse has season-level data for targets going back to the 1999 season.