Derek Carr threw for 513 yards when scoring 4+ passing touchdowns and throwing exactly 0 interceptions against the Buccaneers on October 30, 2016.

who was the last player with 500 pass yds, 4 pass td, 0 int in a game
Interpreted as:
Who was the last player with 500 or more pass yds, 4 or more pass td, 0 passing int in a game?
Derek CarrDerek Carr10/30/2016OAKOAK@TBTB51340405967.
Ben RoethlisbergerBen Roethlisberger10/26/2014PITPITvsINDIND52260404981.610.712.20.000150.6
Y.A. TittleY.A. Tittle10/28/1962NYGNYGvsWASWAS50570273969.212.917.90.0151.4
Results may be incomplete. StatMuse has complete game-level data for intercepted passes, passing touchdowns, and passing yards going back to the 1950 season.