Ron Hextall has the most career games by a Flyers goalie versus the Penguins, with 35 games.

flyers goalie most regular-season games in a career vs penguins

	NAME	GP	GS	W	L	T	OTL	SA	SV	SV%	GA	GAA	SHO	MIN
1	Ron Hextall R. Hextall	35	5	18	13	3		890	785	.882	105	3.15	0	1999
2	Bernie Parent B. Parent	32		18	8	6		956	894	.935	62	1.94	9	1918
3	Doug Favell D. Favell	20		7	7	6		662	619	.935	43	2.21	2	1166
4	Bob Froese B. Froese	16		15	0	0		438	403	.920	35	2.28	0	921
5	Carter Hart C. Hart	14	13	5	6	0	2	429	386	.900	43	3.30	0	782
6	Martin Biron M. Biron	14	14	7	5	0	2	362	323	.892	39	2.89	1	810
7	Brian Boucher B. Boucher	14	11	5	4	2	1	315	275	.873	40	3.29	1	729
8	Pete Peeters P. Peeters	14		7	3	1		368	338	.918	30	2.34	2	770
9	Steve Mason S. Mason	13	13	7	4	0	0	375	348	.928	27	2.26	2	716
10	Antero Niittymaki A. Niittymaki	13	12	4	5	0	3	365	314	.860	51	4.19	0	731
11	Ken Wregget K. Wregget	12		5	5	1		334	291	.871	43	4.03	0	640
12	Pelle Lindbergh P. Lindbergh	12		8	3	1		360	324	.900	36	3.06	1	705
13	Robert Esche R. Esche	11	9	4	3	2	0	246	218	.886	28	2.70	0	622
14	Roman Cechmanek R. Cechmanek	10	9	6	3	0	0	185	166	.897	19	2.27	1	501
15	Brian Elliott B. Elliott	9	9	3	4	0	2	262	227	.866	35	4.20	1	500
16	Sergei Bobrovsky S. Bobrovsky	9	8	5	3	0	1	261	237	.908	24	2.84	0	508
17	Tommy Soderstrom T. Soderstrom	8		1	5	0		196	163	.832	33	5.78	0	343
18	Dominic Roussel D. Roussel	8		1	2	2		191	165	.864	26	4.58	0	341
19	Ilya Bryzgalov I. Bryzgalov	7	7	3	1	0	1	189	169	.894	20	3.17	0	379
20	Wayne Stephenson W. Stephenson	7		4	1	1		183	167	.913	16	2.53	1	380
21	Ray Emery R. Emery	6	5	4	2	0	0	152	137	.901	15	2.79	0	323
22	John Vanbiesbrouck J. Vanbiesbrouck	6	5	4	0	1	0	119	110	.924	9	1.77	0	305
23	Bobby Taylor B. Taylor	6		1	4	0		174	147	.845	27	5.77	0	281
24	Garth Snow G. Snow	5		2	3	0		138	121	.877	17	4.19	0	244
25	Rick St. Croix R. St. Croix	5		3	1	1		116	101	.871	15	3.00	0	300