Wayne Gretzky has collected the most career points against the Penguins, with 124 points.

Interpreted as:

most points by a player against penguins all-time

	NAME	P	GP	G	A	+/-	PIM	PPG	PPA	SHG	SHA	GWG	OTG	S	S%	FOW	FO	FOW%	HIT	BKS	TKA	GVA	TOI/GP
1	Wayne Gretzky W. Gretzky	124	57	44	80	+52	14	7	28	4	6	8	0	212	20.8
2	Mark Messier M. Messier	113	85	37	76	+17	153	12	20	2	3	4	0	232	15.9	205	371	55.3	6	6	16	10	19:59
3	Bobby Clarke B. Clarke	108	76	44	64	+69	69	9	15	6	5	6	1	202	21.8
4	Bryan Trottier B. Trottier	105	82	47	58	+33	58	18	22	2	1	5	0	214	22.0
5	Marcel Dionne M. Dionne	103	82	41	62	+7	40	8	19	2	0	4	0	343	12.0
6	Mike Gartner M. Gartner	102	94	56	46	+4	114	20	18	2	0	6	1	360	15.6
7	Guy Lafleur G. Lafleur	101	70	46	55	+49	25	12	18	1	0	11	0	241	19.1
8	Brian Leetch B. Leetch	92	76	19	73	+9	43	10	42	3	1	1	0	247	7.7	0	0		19	47	21	15	27:37
9	Gilbert Perreault G. Perreault	90	69	39	51	+21	16	11	14	0	1	10	0	193	20.2
10	Brad Park B. Park	90	64	31	59	+64	90	15	24	2	1	6	0	215	14.4
11	Ray Bourque R. Bourque	85	74	21	64	+20	63	8	32	3	3	3	0	313	6.7	0	0		4	5	3	2	28:37
12	Phil Esposito P. Esposito	84	65	40	44	+11	54	16	16	1	0	8	0	288	13.9
13	Darryl Sittler D. Sittler	83	71	37	46	+6	69	10	11	0	1	6	0	270	13.7
14	Mark Recchi M. Recchi	81	78	24	57	-13	36	5	28	3	0	3	0	188	12.8	36	67	53.7	45	11	17	22	19:16
15	Mats Sundin M. Sundin	81	54	38	43	+19	32	9	13	3	1	6	1	162	23.5	344	638	53.9	20	13	5	12	19:50
16	Kirk Muller K. Muller	81	80	28	53	0	120	17	15	0	2	5	0	198	14.1	5	9	55.6	4	2	1	0	10:58
17	Rod Brind'Amour R. Brind'Amour	80	79	28	52	-8	49	10	24	0	1	7	1	139	20.1	519	812	63.9	27	17	15	18	21:04
18	Adam Oates A. Oates	79	61	20	59	-22	12	6	30	0	2	2	2	124	16.1	218	379	57.5	2	6	8	14	23:13
19	Jean Ratelle J. Ratelle	77	67	31	46	+33	12	6	12	0	0	5	0	185	16.8
20	Mike Ridley M. Ridley	76	62	33	43	-2	26	14	7	0	3	3	0	129	25.6
21	Pat LaFontaine P. LaFontaine	76	67	37	39	-4	30	17	16	1	0	3	0	223	16.6
22	Alex Ovechkin A. Ovechkin	75	77	42	33	+4	48	22	12	1	0	3	0	364	11.5	3	13	23.1	275	38	30	51	21:10
23	Mike Bossy M. Bossy	73	53	42	31	+13	12	17	17	2	1	10	1	195	21.5
24	Denis Potvin D. Potvin	73	74	11	62	+34	119	8	28	0	2	2	0	211	5.2
25	Claude Giroux C. Giroux	72	67	21	51	+7	30	6	23	2	0	7	2	171	12.3	677	1,209	56.0	58	28	32	21	20:09