The Seattle Mariners decisively defeated the Boston Red Sox, 5 to 2, on July 22, 2006.

Home run by Mike Lowell.

1

0

Single by Ichiro Suzuki; Yuniesky Betancourt and Carl Everett scored.

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2

Single by David Ortiz; Coco Crisp scored.

2

2

Kenji Johjima hit ground ball; error by Alex Gonzalez; Eduardo Perez scored.

2

3

Single by Eduardo Perez; Adrian Beltre and Willie Bloomquist scored.

2

5