Deshaun Watson has a passer rating of 99.1 with 5,256 yards, 30 touchdowns and 11 interceptions in 21 games without Will Fuller in his career.
| NAME | DATE | TM | OPP | CMP | ATT | PCT | YDS | AVG | TD | TD% | INT | INT% | SCK | SCKY | RATE | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
 | Deshaun Watson | 9/10/2017 |  HOU | vs |  JAX | 12 | 23 | 52.2 | 102 | 4.4 | 1 | 4.3 | 1 | 4.3 | 4 | 21 | 60.4 |
| | Deshaun Watson | 9/14/2017 | HOU | @ |  CIN | 15 | 24 | 62.5 | 125 | 5.2 | 0 | 0.0 | 0 | 0.0 | 3 | 27 | 75.9 |
| | Deshaun Watson | 9/24/2017 | HOU | @ |  NE | 22 | 33 | 66.7 | 301 | 9.1 | 2 | 6.1 | 2 | 6.1 | 2 | 9 | 90.6 |
| | Deshaun Watson | 9/9/2018 | HOU | @ | NE | 17 | 34 | 50.0 | 176 | 5.2 | 1 | 2.9 | 1 | 2.9 | 3 | 18 | 62.9 |
| | Deshaun Watson | 11/4/2018 | HOU | @ |  DEN | 17 | 24 | 70.8 | 213 | 8.9 | 2 | 8.3 | 0 | 0.0 | 4 | 21 | 125.9 |
| | Deshaun Watson | 11/18/2018 | HOU | @ |  WAS | 16 | 24 | 66.7 | 208 | 8.7 | 1 | 4.2 | 2 | 8.3 | 3 | 27 | 72.9 |
| | Deshaun Watson | 11/26/2018 | HOU | vs |  TEN | 19 | 24 | 79.2 | 210 | 8.8 | 2 | 8.3 | 0 | 0.0 | 4 | 29 | 130.9 |
| | Deshaun Watson | 12/2/2018 | HOU | vs |  CLE | 22 | 31 | 71.0 | 224 | 7.2 | 1 | 3.2 | 0 | 0.0 | 4 | 27 | 102.1 |
| | Deshaun Watson | 12/9/2018 | HOU | vs |  IND | 27 | 38 | 71.1 | 267 | 7.0 | 1 | 2.6 | 0 | 0.0 | 5 | 41 | 99.3 |
| | Deshaun Watson | 12/15/2018 | HOU | @ |  NYJ | 22 | 28 | 78.6 | 294 | 10.5 | 2 | 7.1 | 0 | 0.0 | 6 | 55 | 134.2 |
| | Deshaun Watson | 12/23/2018 | HOU | @ |  PHI | 29 | 40 | 72.5 | 339 | 8.5 | 2 | 5.0 | 0 | 0.0 | 4 | 30 | 114.5 |
| | Deshaun Watson | 12/30/2018 | HOU | vs | JAX | 25 | 35 | 71.4 | 234 | 6.7 | 0 | 0.0 | 0 | 0.0 | 6 | 26 | 89.5 |
| | Deshaun Watson | 10/27/2019 | HOU | vs |  OAK | 27 | 39 | 69.2 | 279 | 7.2 | 3 | 7.7 | 0 | 0.0 | 3 | 21 | 115.2 |
| | Deshaun Watson | 11/3/2019 | HOU | @ | JAX | 22 | 28 | 78.6 | 201 | 7.2 | 2 | 7.1 | 0 | 0.0 | 1 | 7 | 120.4 |
| | Deshaun Watson | 11/17/2019 | HOU | @ |  BAL | 18 | 29 | 62.1 | 169 | 5.8 | 0 | 0.0 | 1 | 3.4 | 6 | 49 | 63.7 |
| | Deshaun Watson | 12/8/2019 | HOU | vs | DEN | 28 | 50 | 56.0 | 292 | 5.8 | 1 | 2.0 | 2 | 4.0 | 3 | 12 | 63.1 |
| | Deshaun Watson | 12/6/2020 | HOU | vs | IND | 26 | 38 | 68.4 | 341 | 9.0 | 0 | 0.0 | 1 | 2.6 | 5 | 33 | 85.5 |
| | Deshaun Watson | 12/13/2020 | HOU | @ |  CHI | 21 | 30 | 70.0 | 219 | 7.3 | 1 | 3.3 | 0 | 0.0 | 6 | 52 | 101.9 |
| | Deshaun Watson | 12/20/2020 | HOU | @ | IND | 33 | 41 | 80.5 | 373 | 9.1 | 2 | 4.9 | 0 | 0.0 | 5 | 31 | 120.8 |
| | Deshaun Watson | 12/27/2020 | HOU | vs | CIN | 24 | 33 | 72.7 | 324 | 9.8 | 3 | 9.1 | 0 | 0.0 | 1 | 2 | 133.9 |
| | Deshaun Watson | 1/3/2021 | HOU | vs | TEN | 28 | 39 | 71.8 | 365 | 9.4 | 3 | 7.7 | 1 | 2.6 | 4 | 24 | 115.9 |
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