Barry Sanders had the most games with 150+ rushing yards, with 25 games.

nfl most games with 150 rushing yards player
Interpreted as:
NFL most regular-season games with 150 or more rushing yards player
SandersPaytonPetersonSmithDickersonTomlinsonSimpsonCampbellBrownGreenDavisFaulkAlexanderHolmesMcCoyLewisDorsettHenryCharlesJohnsonJohnsonTaylor252019181816161414121212111110101099999
NAMEGPRUSH YDSATTRUSH AVGRUSH YDS/GRUSH TDREC YDSRECTRGREC AVGREC YDS/GREC TD
Barry SandersBarry Sanders254,4646147.3178.633312456.912.51
Walter PaytonWalter Payton203,5465766.2177.327287387.614.40
Adrian PetersonAdrian Peterson193,5645136.9187.62522936556.412.11
Emmitt SmithEmmitt Smith183,0014856.2166.7272745505.015.21
Eric DickersonEric Dickerson183,2155266.1178.6272542410.614.10
LaDainian TomlinsonLaDainian Tomlinson163,0294307.0189.334404731005.525.32
O.J. SimpsonO.J. Simpson163,1064357.1194.121138159.28.60
Earl CampbellEarl Campbell142,5764685.5184.0212883.52.00
Jim BrownJim Brown142,5443427.4181.7213092611.922.13
Ahman GreenAhman Green122,0082717.4167.31123637496.419.72
Terrell DavisTerrell Davis122,2023506.3183.517223278.318.62
Marshall FaulkMarshall Faulk122,2042907.6183.71858162649.448.45
Shaun AlexanderShaun Alexander111,9883216.2180.718519155.74.61
Priest HolmesPriest Holmes111,9022926.5172.91737540449.434.14
LeSean McCoyLeSean McCoy101,6682566.5166.8117616194.87.60
Jamal LewisJamal Lewis101,9562787.0195.61212414198.912.40
Tony DorsettTony Dorsett101,6542227.5165.4994137.29.40
Derrick HenryDerrick Henry91,8212337.8202.3228510158.59.40
Jamaal CharlesJamaal Charles91,6962068.2188.41016920308.518.81
Chris JohnsonChris Johnson91,5861928.3176.21216422317.518.21
Larry JohnsonLarry Johnson91,5662825.6174.0187613225.88.41
Fred TaylorFred Taylor91,5882476.4176.41511919246.313.21
Corey DillonCorey Dillon91,7572606.8195.2149416225.910.41
Curtis MartinCurtis Martin91,5722705.8174.7820727257.723.01
Arian FosterArian Foster81,3492166.2168.61210118285.612.61
StatMuse has game-level data for rushing yards going back to the 1960 season.

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