London Fletcher had the most games with 5+ tackles, with 132 games.

nfl most games with 5 tackles player
Interpreted as:
NFL most regular-season games with 5 or more tackles player
FletcherDansbyLewisBrookingUrlacherJohnsonBriggsBetheaPoslusznyDavidWeddleEdwardsFarriorWinfieldJacksonWillisGreenwayWagnerDavisBulluckBarberRyans13212211311211110710410310193929089878584838282828280
NAMEGPTKLASTCOMBSCKSCKYINTINT YDSINT TDFFFRFR TD
London FletcherLondon Fletcher1329733961,36920.5132.51310321481
Karlos DansbyKarlos Dansby1228271931,02032.0215.51219331360
Ray LewisRay Lewis1138422841,12622.515219335314110
Keith BrookingKeith Brooking11277819697414.096121730570
Brian UrlacherBrian Urlacher11178919798626.515514189111122
Derrick JohnsonDerrick Johnson10775012487421.5137820231870
Lance BriggsLance Briggs10473815589310.0661119141461
Antoine BetheaAntoine Bethea1036811708518.056121071740
Paul PoslusznyPaul Posluszny1017612421,00314.093.5121311730
Lavonte DavidLavonte David9366719085719.51437110117120
Eric WeddleEric Weddle926101387485.027.5111782661
Donnie EdwardsDonnie Edwards906612118728.547172072951
James FarriorJames Farrior8961320782019.5126613401130
Antoine WinfieldAntoine Winfield87617937106.5521415221171
D'Qwell JacksonD'Qwell Jackson8559424583915.5106.56601660
Patrick WillisPatrick Willis8464015979918.5116.5612921650
Chad GreenwayChad Greenway8357121078113.5714250660
Bobby WagnerBobby Wagner8256827684417.5115.541171441
Thomas DavisThomas Davis8255116972016.510485401110
Keith BulluckKeith Bulluck8259719078713.595.5910001253
Ronde BarberRonde Barber825477962610.0582048051131
DeMeco RyansDeMeco Ryans8058314172410.5102.56620291
Charles TillmanCharles Tillman80540666063.0142037933150
Nick BarnettNick Barnett8054519273715.5114.571721160
Will WitherspoonWill Witherspoon805299762618.51145532910
StatMuse has game-level data for tackles going back to the 2001 season.

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