Ron Dayne has rushed for the most career yards in the Big 10, with 6,397 yards.

	NAME	RUSH YDS	GP	ATT	YPC	RUSH YDS/G	RUSH TD	REC YDS	REC	TRG	AVG	REC YDS/G	REC TD
1	Ron Dayne R. Dayne	6,397	43	1,115	5.7	148.8	63	304	31		9.8	7.1	0
2	Jonathan Taylor J. Taylor	6,174	41	926	6.7	150.6	50	407	42	67	9.7	9.9	5
3	Justin Jackson J. Jackson	5,440	51	1,142	4.8	106.7	41	858	122	165	7.0	16.8	1
4	Archie Griffin A. Griffin	5,177	42	845	6.1	123.3	25	286	25		11.4	6.8	1
5	Montee Ball M. Ball	5,140	49	924	5.6	104.9	77	598	59		10.1	12.2	6
6	Michael Hart M. Hart	5,040	43	1,015	5.0	117.2	41	566	67		8.4	13.2	2
7	Anthony Thompson A. Thompson	4,965	44	1,089	4.6	112.8	64	713	94		7.6	16.2	1
8	Melvin Gordon M. Gordon	4,915	43	631	7.8	114.3	45	228	22		10.4	5.3	4
9	Anthony Davis A. Davis	4,676	40	908	5.1	116.9	42	198	22		9.0	5.0	0
10	Mohamed Ibrahim M. Ibrahim	4,668	40	867	5.4	116.7	53	145	22	28	6.6	3.6	0
11	Ameer Abdullah A. Abdullah	4,588	53	813	5.6	86.6	39	690	73		9.5	13.0	7
12	Darrell Thompson D. Thompson	4,518	44	911	5.0	102.7	40	337	47		7.2	7.7	3
13	Lorenzo White L. White	4,513	43	991	4.6	105.0	41	268	36		7.4	6.2	0
14	Denard Robinson D. Robinson	4,498	48	722	6.2	93.7	42	31	3		10.3	0.6	0
15	J.K. Dobbins	4,459	42	725	6.2	106.2	38	645	71	91	9.1	15.4	5
16	Javon Ringer J. Ringer	4,398	45	843	5.2	97.7	34	719	96		7.5	16.0	1
17	Damien Anderson D. Anderson	4,336	42	935	4.6	103.2	37	490	54		9.1	11.7	0
18	Kaytron Allen K. Allen	4,180	54	769	5.4	77.4	39	490	70	100	7.0	9.1	4
19	Tico Duckett T. Duckett	4,176	44	824	5.1	94.9	26	266	41		6.5	6.0	2
20	Rodney Smith R. Smith	4,122	53	879	4.7	77.8	29	521	65	84	8.0	9.8	0
21	Anthony Thomas A. Thomas	4,098	44	846	4.8	93.1	49	750	78		9.6	17.0	1
22	Robert Holcombe R. Holcombe	4,059	42	931	4.4	96.6	25	619	72		8.6	14.7	3
23	James White J. White	4,015	52	644	6.2	77.2	45	670	73		9.2	12.9	3
24	Ezekiel Elliott E. Elliott	3,961	36	592	6.7	110.0	43	449	58	66	7.7	12.5	1
25	Jamie Morris J. Morris	3,943	45	745	5.3	87.6	21	703	91		7.7	15.6	3