Donnel Pumphrey rushed for the most yards in 2016, with 2,133 yards.

	NAME	RUSH YDS	SEASON	TM	GP	ATT	YPC	RUSH YDS/G	RUSH TD	REC YDS	REC	TRG	AVG	REC YDS/G	REC TD
1	Donnel Pumphrey D. Pumphrey	2,133	2016	SDSU	14	349	6.1	152.4	17	231	27	39	8.6	16.5	0
2	D'Onta Foreman D. Foreman	2,028	2016	TEX	11	323	6.3	184.4	15	75	7	9	10.7	6.8	0
3	Brian Hill B. Hill	1,860	2016	WYO	14	349	5.3	132.9	22	67	8	14	8.4	4.8	0
4	Aaron Jones A. Jones	1,773	2016	UTEP	12	229	7.7	147.8	17	233	28	35	8.3	19.4	3
5	Dalvin Cook D. Cook	1,765	2016	FSU	13	288	6.1	135.8	19	488	33	48	14.8	37.5	1
6	Jeremy McNichols J. McNichols	1,709	2016	BSU	13	314	5.4	131.5	23	474	37	42	12.8	36.5	4
7	James Flanders J. Flanders	1,629	2016	TLSA	13	258	6.3	125.3	18	17	3	5	5.7	1.3	0
8	Anthony Wales A. Wales	1,621	2016	WKU	13	237	6.8	124.7	27	323	30	39	10.8	24.8	2
9	Christian McCaffrey C. McCaffrey	1,603	2016	STAN	11	253	6.3	145.7	13	310	37	48	8.4	28.2	3
10	Lamar Jackson L. Jackson	1,571	2016	LOU	13	260	6.0	120.8	21
11	I'Tavius Mathers I. Mathers	1,561	2016	MTSU	13	232	6.7	120.1	17	633	66	79	9.6	48.7	3
12	Quinton Flowers Q. Flowers	1,530	2016	USF	13	198	7.7	117.7	18	-3	1	1	-3.0	-0.2	0
13	Justin Jackson J. Jackson	1,524	2016	NW	13	298	5.1	117.2	15	219	35	53	6.3	16.8	0
14	Saquon Barkley S. Barkley	1,496	2016	PSU	14	272	5.5	106.9	18	402	28	38	14.4	28.7	4
15	Kareem Hunt K. Hunt	1,475	2016	TOL	13	262	5.6	113.5	10	403	41	44	9.8	31.0	1
16	Ito Smith I. Smith	1,459	2016	USM	13	265	5.5	112.2	17	459	43	64	10.7	35.3	2
17	D'Angelo Brewer D. Brewer	1,435	2016	TLSA	12	264	5.4	119.6	7	19	5	7	3.8	1.6	1
18	Joe Williams J. Williams	1,407	2016	UTAH	9	210	6.7	156.3	10	107	9	13	11.9	11.9	0
19	Jalin Moore J. Moore	1,402	2016	APP	13	237	5.9	107.8	10	32	5	8	6.4	2.5	0
20	Derrius Guice D. Guice	1,387	2016	LSU	12	183	7.6	115.6	15	106	9	15	11.8	8.8	1
21	Nick Fitzgerald N. Fitzgerald	1,385	2016	MSST	13	195	7.1	106.5	16	9	1	1	9.0	0.7	0
22	Corey Clement C. Clement	1,375	2016	WIS	13	314	4.4	105.8	15	132	12	14	11.0	10.2	0
23	Jamaal Williams J. Williams	1,375	2016	BYU	11	234	5.9	125.0	12	80	7	12	11.4	7.3	0
24	Myles Gaskin M. Gaskin	1,373	2016	WASH	14	237	5.8	98.1	10	137	19	26	7.2	9.8	1
25	Rawleigh Williams III R. Williams III	1,360	2016	ARK	13	245	5.6	104.6	12	220	15	22	14.7	16.9	1