Since 2000, Case Keenum has the most passing yards, with 19,217 yards.

Interpreted as:

most college passing yards by a player since 2000

	NAME	YDS	GP	CMP	ATT	PCT	AVG	YDS/G	TD	INT	RTG	TD%	INT%	SCK	SCKY
1	Case Keenum C. Keenum	19,217	57	1,546	2,229	69.4	8.6	337.1	155	46	160.6	7.0	2.1
2	Dillon Gabriel D. Gabriel	18,722	64	1,376	2,111	65.2	8.9	292.5	155	32	160.9	7.3	1.5	111	676
3	Timmy Chang T. Chang	17,072	53	1,388	2,436	57.0	7.0	322.1	117	80	125.1	4.8	3.3
4	Landry Jones L. Jones	16,646	52	1,388	2,183	63.6	7.6	320.1	123	52	141.5	5.6	2.4
5	Graham Harrell G. Harrell	15,793	45	1,403	2,010	69.8	7.9	351.0	134	34	154.4	6.7	1.7
6	Sam Hartman S. Hartman	15,656	60	1,136	1,898	59.9	8.2	260.9	134	49	147.3	7.1	2.6	129	804
7	Bo Nix B. Nix	15,352	61	1,286	1,936	66.4	7.9	251.7	113	26	149.6	5.8	1.3	60	388
8	Will Rogers W. Rogers	14,773	54	1,521	2,187	69.5	6.8	273.6	108	35	139.4	4.9	1.6	110	779
9	Kellen Moore K. Moore	14,667	53	1,157	1,658	69.8	8.8	276.7	142	28	169.0	8.6	1.7
10	Baker Mayfield B. Mayfield	14,607	48	1,026	1,497	68.5	9.8	304.3	131	30	175.4	8.8	2.0	108	664
11	Luke Falk L. Falk	14,481	43	1,403	2,054	68.3	7.1	336.8	119	39	142.8	5.8	1.9	124	859
12	Seth Henigan S. Henigan	14,278	50	1,148	1,792	64.1	8.0	285.6	104	31	146.7	5.8	1.7	96	542
13	Colt Brennan C. Brennan	14,193	38	1,115	1,584	70.4	9.0	373.5	131	42	167.6	8.3	2.7
14	Rakeem Cato R. Cato	14,079	53	1,153	1,838	62.7	7.7	265.6	131	44	145.8	7.1	2.4
15	Holton Ahlers H. Ahlers	13,936	55	1,127	1,857	60.7	7.5	253.4	97	37	137.0	5.2	2.0	104	707
16	Michael Penix Jr. M. Penix Jr.	13,741	48	1,067	1,685	63.3	8.2	286.3	96	34	146.6	5.7	2.0	32	223
17	Brett Rypien B. Rypien	13,703	51	1,050	1,648	63.7	8.3	268.7	91	29	148.3	5.5	1.8	92	564
18	Mason Rudolph M. Rudolph	13,618	42	915	1,447	63.2	9.4	324.2	92	26	159.7	6.4	1.8	92	539
19	Sean Mannion S. Mannion	13,600	47	1,187	1,838	64.6	7.4	289.4	83	54	135.8	4.5	2.9
20	Philip Rivers P. Rivers	13,484	49	1,087	1,711	63.5	7.9	275.2	95	34	144.1	5.6	2.0
21	Corey Robinson C. Robinson	13,472	48	1,179	1,823	64.7	7.4	280.7	81	48	136.1	4.4	2.6
22	Colt McCoy C. McCoy	13,253	53	1,157	1,645	70.3	8.1	250.1	112	45	155.0	6.8	2.7
23	Aaron Murray A. Murray	13,166	52	921	1,478	62.3	8.9	253.2	121	41	158.6	8.2	2.8
24	Kevin Kolb K. Kolb	12,964	50	964	1,565	61.6	8.3	259.3	85	31	145.1	5.4	2.0
25	Dan Lefevour D. Lefevour	12,905	53	1,171	1,763	66.4	7.3	243.5	102	36	142.9	5.8	2.0